Overview
Antioxidant supplements and drug interactions concern the use of dietary antioxidant compounds, such as vitamins C and E, carotenoids, and other micronutrients, and how these supplements may influence, or be influenced by, concurrent medications. Antioxidants counter oxidative stress, the imbalance between reactive oxygen species and the body's capacity to neutralize them, which is implicated in conditions including metabolic syndrome, cardiovascular disease, and type 2 diabetes. Supplementation is studied as a way to restore antioxidant defenses and ameliorate disease features such as insulin resistance, dyslipidemia, and endothelial dysfunction. This topic matters because supplements are widely used yet can have variable and dose-dependent effects, and because their pharmacological activity raises the possibility of interactions with prescribed drugs that share metabolic pathways or therapeutic targets. Key aspects include the biochemical basis of antioxidant action, the evidence from clinical and dietary studies, appropriate dosing, and the safety considerations of combining supplements with medication. Related open-access research available here examines the potential of antioxidant micronutrients in the management of metabolic syndrome, including evidence on supplements such as vitamin E and their role in addressing oxidative stress and associated cardiovascular risk.
Research published in this journal
6 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Antioxidant Activity of Surinamese Medicinal Plants with Adaptogenic Properties and Correlation with Total Phenolic Contents
The Total Antioxidant Capacity of Foods: A Reappraisal. Application to Commercial Orange Juices
Antioxidant Protection of Donor Packed Red Blood Cells using Mexidol
Anti-Oxidant Phytochemicals as Potential Treatments for Age-Related Macular Degeneration
How this research is being cited
The 6 articles above have been cited 41 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.
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2026 · Cellular Immunology
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2026 · Cellular Immunology
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2025 · Faculty of Natural and Applied Sciences Journal of Applied and Physical Sciences
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2024 · Nutrients
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2024 · Indian Journal of Animal Research
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H. Sharebiani et al. · 2024 · Nutrients
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2023 · Biochemistry
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2023 · Biochemistry
A sample of recent works citing this journal's research on Antioxidant Supplements and Drug Interactions, linking to each citing work.