Aims and Scope
- Open access · CC BY 4.0
- ISSN 2998-4211
- Published by Open Access Pub
JALR publishes research on Alzheimer’s disease and related dementias across the whole disease continuum: how the disease arises, how it is detected, how it is treated and how people living with it are cared for.
Across the disease continuum
Alzheimer’s research is usually described as a continuum, from the first biological change to diagnosis, treatment and long-term care. JALR is organized along that continuum, and every part of it is within scope. The topics shown are illustrative and do not form a closed list.
- 01
Mechanisms
How Alzheimer’s disease and related dementias arise and progress.
- Molecular and cellular pathophysiology
- Genetics and risk
- Neuroinflammation
- Cellular and animal models
- 02
Detection
How the disease is recognized, measured and predicted.
- Biomarkers
- Neuroimaging
- Cognitive assessment
- Risk prediction
- 03
Treatment
How the disease is treated and how treatments are evaluated.
- Clinical trials
- Drug discovery
- Therapeutic development
- Disease-modifying approaches
- 04
Care
How people living with dementia and their families are supported.
- Caregiver outcomes
- Quality of life
- Non-drug interventions
- Digital health and AI in care
What each area covers
Mechanisms
Studies of the molecular, cellular, genetic and systems-level processes behind Alzheimer’s disease and related dementias, including protein pathology, synaptic and vascular change, neuroinflammation, genetic risk, and cellular and animal models.
Detection
Biomarker discovery and validation, neuroimaging, cognitive and functional assessment, diagnostic and prognostic tools, and studies of risk, incidence and prevalence in clinical and population samples.
Treatment
Clinical trials, drug discovery and development, repurposed and disease-modifying approaches, and pharmacological and neuromodulatory interventions, including pharmacovigilance and outcome measurement.
Care
Caregiver outcomes, quality of life, care pathways, non-drug interventions, digital health and artificial intelligence in dementia care, health services research, health economics, and community-based and public-health research.
Related dementias and neighboring fields
Related dementias include vascular, Lewy body, frontotemporal and mixed dementia. Work on other neurodegenerative or neurological conditions is considered when it bears directly on Alzheimer’s disease or related dementias, for example through shared mechanisms, differential diagnosis or comorbidity.
Interdisciplinary teams across neurology, geriatrics, psychiatry, psychology, nursing, genetics, imaging, pharmacology, health economics and public health are encouraged. Replication studies and well-explained negative results are welcome when they strengthen the evidence base.
Authors who are unsure whether a topic fits are invited to write to the editorial office before submitting.
What the journal publishes
The same list applies on every page of the journal website.
- Original Research (including clinical trials)
- Systematic Review and Meta-Analysis
- Review
- Mini-Review
- Methods and Protocols
- Short Communication
- Data Note
- Case Report
- Perspective
- Commentary
- Editorial
- Letter to the Editor
Requirements for each type are set out in the Instructions for Authors.
Review, ethics and open access
All submissions undergo initial editorial screening. Manuscripts that meet the journal’s scope and minimum requirements proceed to independent peer review.
Single-blind by default; double-blind review is available on request. Manuscripts that proceed to external peer review are normally evaluated by at least two independent subject-matter experts.
Editorial decisions are based on scope, scientific quality, methodological rigor, ethical compliance, reporting quality, and relevance to the journal.
Studies involving human participants require ethical review and, where applicable, informed consent. Animal studies are reported with reference to the ARRIVE guidelines. Every empirical research manuscript includes a data-availability statement.
All articles are open access under CC BY 4.0. The article processing charge is USD 1,200, payable only after acceptance; withdrawal after submission is subject to the journal's withdrawal policy. See Article Processing Charges.
Choose a submission route
ManuscriptZone
The primary route. Create an account, submit the manuscript and follow its progress online.
Open ManuscriptZoneSimple manuscript submission form
The alternative route, with JALR preselected as the journal.
Open the formEditorial office email
The assisted route, for authors who need help to submit.
info@openaccesspub.org
Authors must use only one submission route for the same manuscript.