Search results for “Dose”

About 99 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Dose — open any to read the full text, or download the PDF or XML.

Stratified Analysis of Factors Associated With Mortality in Patients With COVID-19 Based on Cancer and Diabetes

Feb 2024 DOI 10.14302/issn.2693-1176.ijgh-23-4879
Shih-Ping LinCorresponding author

Background Cancer and diabetes are risk factors for COVID-19 mortality rates. Remdesivir, dexamethasone, and vaccines are used to improve clinical outcomes. We aimed to evaluate the factors associated with COVID-19 mortality rates. Methods This retrospective study enrolled moderate to critical COVID…

The Application of Immunoglobulins Immune Response in the Discovery and Development of Safe Therapeutic Agents: A Review Article

Jan 2024 DOI 10.14302/issn.2328-0182.japst-23-4771
Yilkal Tariku BelayCorresponding author

Background Immunoglobulins are bio-receptors found embedded in the cell membrane with a biological role that detects the harmful molecules of a test compound. These bio-receptors interface between a biological system and its external environment that transduce information to the effector via interme…

Scrutinizing Local Probiotic Supplements and Drinks Available in the Bangladesh Market

Jan 2024 DOI 10.14302/issn.2379-7835.ijn-23-4802
Fatema AkterCorresponding author

The host's health may benefit from the probiotic microorganisms found in many products available on the market. In addition to food, these products include dietary supplements, food for special medical purposes, medicines, cosmetics, and medical devices. These products have anywhere from one to a do…

Histomorphomertric Analysis Of Hormonal Contraceptive Pills On Anterior Pituitary Gland In Female Wister Rats

Oct 2023 DOI 10.14302/issn.3070-2313.jeh-23-4547
S. A AbubakarCorresponding author

Millions of women use hormonal contraceptive pills around the world and though the physical effects are thoroughly described in the literature and clinical setting. The psychological effects have been largely ignored until recently. Recent studies have found that the use of hormonal contraceptives h…

Study of Anti-Inflammatory Effects of Black Cumin (Nigella Sativa) and Honey on Mice (Mus Musculus)

Aug 2023 DOI 10.14302/issn.2694-2275.jzr-23-4642
Tayyaba ZahoorCorresponding author

The study was conducted to determine the effect of Nigella sativa (Kalonji) and Honey as an anti-inflammatory agent for humans and animals. The study was carried out on 20 Albino Mice of almost equal size and weight. All the mice were given 5% solution of formalin in a dose of 0.5ml injection in the…

Pyrexia And Liver Injury After A Second SARS-CoV-2 Vaccination: Macrophage Activation Manifested In Liver

Aug 2023 DOI 10.14302/issn.2692-1537.ijcv-23-4679
Tomiko RyuCorresponding author

Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-Co V-2) has contributed to control of the coronavirus disease 2019 (COVID-19). On the other side, vaccination of SARS-CoV-2 could trigger autoimmune or inflammatory diseases. We present a 50-year-old female with well-controlle…

Baroreflex Sensitivity, Cardiac and Kidney Remodeling and Deterioration in Vasoactive Substances Content in Blood in Experimental Model of Renovascular Hypertension. Action of Natural Flavone, Luteolin

May 2023 DOI 10.14302/issn.2574-4488.jna-23-4545
N.A. PapiashviliCorresponding author

This study aimed to analyze pharmacological actions of phenolic compound luteolin on the renal and cardiac hypertrophy, blood pressure (BP), baroreflex sensitivity (BRS), levels of epoxyeicosatrienoic acids (EETs), prostaglandin E-2 (PGE-2) and endothelin-1 (E1) in plasma in the 2 kidney - 1 clip (2…

Dual Energy Computed Tomography and Effect on the Management of Uric Acid Renal Calculi

Mar 2023 DOI 10.14302/issn.2766-8630.jrnm-22-4093
AJ JahangiriCorresponding author

Attenuation differences from 2 x-ray sources allow differentiation and characterization of stone types with similar radiation dose compared to single-energy CT scan. The difference is shown in colours, allowing preoperative prediction and management of stones. We determined the effect of DECT-KUB on…

Safety of BBIBP-CorV (Sinopharm) COVID-19 Vaccination in People With Multiple Sclerosis: A Report From Iran

Mar 2023 DOI 10.14302/issn.2690-4837.ijip-22-4342
Seyed Massood NabaviCorresponding author

Introduction Vaccination against SARS CoV-2 started on March 2020 in Iran and people with multiple sclerosis (pwMS) have a priority to be vaccinated in line of other high-risk population. Up to now, BBIBP-CorV (Sinopharm) is the main vaccine which have been used in Iranian population, and in high ri…

The trajectory of immunoglobulins immune response against the different amounts of xenobiotics matches the trajectory of biological changes associated with ageing: A systematic review

Mar 2023 DOI 10.14302/issn.2474-7785.jarh-22-4381
Yilkal Tariku BelayCorresponding author

Background Ageing is a life process in which progressive molecular, cellular, physiological and anatomical changes manifesting in humans and animals including other organisms lead to the decline of biological functions. Immunoglobulins (Igs) are glycoprotein molecules produced by white blood cells m…

A Wild-plant extract could eliminate infectious-pathogens, Ranyah, KSA

Feb 2023 DOI 10.14302/issn.2576-6694.jbbs-22-4418
Sherifa Mostafa M. SabraCorresponding author

Saudi Arabia is rich in Juniperusprocera Hochst. ex Endl (Cupressaceae) as a medicinal plant. Its known as Arar, its present southwards, KSA. It's used as traditional medicine in the southwestern, KSA. The aim was according to "Saudi Arabian Customs" in using wild-plant extract for treatment and pre…

Effect of Set Size and Fertilizer Type on Off- Season Onion (Allium cepa. L) Production

Dec 2022 DOI 10.14302/issn.2639-3166.jar-22-4300
Elsadig E. E. ElshukryCorresponding author

Two off-season experiments were conducted during 2015/16 and 2017/18 at Shambat Research Station Farm, Khartoum, Sudan, to investigate the effects of large (2-3 cm) and small (1-2 cm) sets size of onion variety Baftaim (S) and two chemical fertilizer (Urea 240 kg/ha) and NPK(15:15:15) (120 kg/ha) in…

Effect of Extracts of Dialium guineense Stem Bark on Lipid Profile and CCl4- Induced Histological Changes in Liver of Wistar Rats

Nov 2022 DOI 10.14302/issn.2835-513X.ijl-22-4266
O.D AbuCorresponding author Department of Biochemistry, Faculty of Life Sciences, University of Benin, Benin City, Nigeria

The present study investigated the effect of aqueous and ethanol extracts of Dialiumguineense stem bark on lipid profile and CCl4- induced histological changes in liver of Wistar rats. Adult male Wistar rats (n = 25) weighing 160 – 180 g (mean weight = 170 ± 10 g) were randomly assigned to five grou…

Histo-Morphological Effect of The Small, Large Intestines and Stomach of Animal Models Treated With Aqueous Extract of Abelmoschus Esculentus

Nov 2022 DOI 10.14302/issn.2641-4538.jphi-22-4235
Kebe E. ObetenCorresponding author

This study investigates the effect of Aqueous extract of abelmoschus esculentus on the microanatomy of the small, large intestine and stomach and the body weight of Wister rats. Twenty-one adults male wistar rats weighing between 100-120 grams were assigned into three groups consisting of seven rats…

Cross-Reactivity between COX-2 Inhibitors in Patients with Cross-Reactive Hypersensitivity to NSAIDs

Sep 2022 DOI 10.14302/issn.2641-4538.jphi-22-4238
Sevim BavbekCorresponding author

The safety of cyclooxygenase (COX)-2 inhibitors has been tested in patients who had cross-reactive hypersensitivity reactions (HSRs) to nonsteroidal anti-inflammatory drugs (NSAIDs). However, these studies have been mainly done before the current classification of NSAID hypersensitivity and cross-re…

Computational Systemic Biology for Toxicity Studies: A Mini Review of Previously Published Articles

Jun 2022 DOI 10.14302/issn.2328-0182.japst-22-4193
Yilkal Tariku BelayCorresponding author

The strategy for safe drug discovery and development has limited clinical success as compared to wasted time and resources annually. This is due to the fact that the results of multiphase preclinical trials are less likely to make an accurate early prediction on the safety of test compounds to progr…

Anti-COVID19 Vaccine among Workers at the Local Health Authority of Rieti (Italy). Study on the Vaccine Efficacy and Seroprevalence Post-Vaccination

Mar 2022 DOI 10.14302/issn.2641-4538.jphi-22-4113
L ProvvidentiCorresponding author Postgraduate School of Public Health, Department of MESVA, University of L’Aquila (Italy).

Objectives Our study aims to determine the trend of the antibody titer and assess the efficacy of the vaccine. Methods It was conducted on 983 healthcare professionals between 27 February 2020 and 22 October 2021 at the Local Health Authority (ASL) of Rieti. Workers voluntarily underwent serological…

Dolutegravir: Pharmacokinetics and Pregnancy Profile

Mar 2022
Gudisa BeredaCorresponding author

Dolutegravir suppresses this integration enzyme, so human immune virus can’t create every greater copies of itself, thus ‘’integrase inhibitor.’’ Dolutegravir is hastily absorbed pursuing oral administration. The median maximum plasma concentration is reached 1.5–2.5 hours after oral uptake with a m…

Challenger and Propose Novel Methods and Techniques for Prevention, Prognosis, Diagnosis, Imaging, Screening, Treatment and Management of Lung Cancer

Feb 2022
Ricardo GobatoCorresponding author

Using samples of small cell lung tumors, a research team led by biologist Dr. Raymond discovered two new ways to induce tumor cell death. By activating ferroptosis, one of two subtypes of tumor cells can be targeted: first, iron-dependent cell death due to oxidative stress, and second, oxidative str…

Characterization of the Vaccine Abdala

Dec 2021 DOI 10.14302/issn.2691-8862.jvat-21-3999
Katia Pino MarreroCorresponding author

Vaccines symbolize the main pandemic control tool in the world, which is why they are the object of study in many investigations. In this work, the Abdala vaccine was characterized in terms of adverse reactions by conducting a survey and statistical processing of the data taken through distribution…

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