Search results for “Pathogen”

About 80 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Pathogen — open any to read the full text, or download the PDF or XML.

Malaria: A Driving Force to the Emergence and the Global Spread of Antibiotics Resistance

Mar 2025 DOI 10.14302/issn.2693-1176.ijgh-25-5429
Rasheed O. MakanjuolaCorresponding author

Malaria and bacteraemia are significant public health concerns and economic threats. In Africa, the intensity for simultaneous transmission and co-infection of Plasmodium spp and other bacteria pathogens are extremely high. It is believed that malaria suppress the immune system and enable the transl…

Genotypic Diversity among Salmonella Typhi Isolated from Children Living in Informal Settlements in Nairobi, Kenya

Sep 2024 DOI 10.14302/issn.2690-4721.ijcm-24-5195
Susan Mutile KavaiCorresponding author

The persistence of multidrug-resistant (MDR) Salmonella Typhi (S. Typhi) is a challenge especially in regions where typhoid is endemic. Surveillance of circulating genotypes of MDR S. Typhi is crucial in typhoid acute cases and carriers. This study aimed to investigate genotypic diversity of S. Typh…

Prevalence and Antifungal Susceptibility of Candida species from patients attending Rivers State University Teaching Hospital, Nigeria

Sep 2024 DOI 10.14302/issn.2690-4721.ijcm-24-5126
D. N Girah.Corresponding author

The development of medical therapy and patients profile has led to a rise in the incidence of nosocomial fungal infection. The frequency of candidiasis has surged worldwide, and the prevalent of healthcare diseases are now Candida species. Candida species causes a range of human infections known as…

A Network Pharmacology-Based Strategy For Predicting Therapy Targets Of Beta-Sitosterol In Treating Diabetic Retinopathy

May 2024 DOI 10.14302/issn.2470-0436.jos-23-4493
Kexin SunCorresponding author

Background Beta-Sitosterol (SIT) is an active TCM compound employed to treat diabetic retinopathy (DR). A network pharmacology approach to understanding the active ingredients and the therapeutic mechanisms underlying DR has not been pursued. Methods The potential targets for DM were identified acco…

Fecal Shedding, Antimicrobial Resistance and In Vitro Biofilm formation on Simulated Gallstones by Salmonella Typhi Isolated from Typhoid Cases and Asymptomatic Carriers in Nairobi, Kenya

Apr 2024 DOI 10.14302/issn.2690-4721.ijcm-24-5030
John S. GunnCorresponding author

Typhoid fever, caused by the human restricted pathogen Salmonella Typhi, remains a major global public health concern. Even after successful treatment, approximately 3-5% of patients with typhoid fail to clear the bacteria within one year and become chronic carriers. Most typhoid carriers have galls…

A Trio Study Showing Novel Gene Mutation In LAMB3 Causing Junctional Epidermolysis Bullosa (Intermediate/ Severe)

Feb 2024
Shaile BandlaCorresponding author

Background Junctional epidermolysis bullosa (JEB) is a type of Epidermolysis Bullosa, a group of genetic conditions that cause the skin to be very fragile and to blister easily. It is categorized into: the Herlitz type and the Non-Herlitz type. JEB is inherited in an autosomal recessive pattern. Mos…

Scrutinizing Local Probiotic Supplements and Drinks Available in the Bangladesh Market

Jan 2024 DOI 10.14302/issn.2379-7835.ijn-23-4802
Fatema AkterCorresponding author

The host's health may benefit from the probiotic microorganisms found in many products available on the market. In addition to food, these products include dietary supplements, food for special medical purposes, medicines, cosmetics, and medical devices. These products have anywhere from one to a do…

Camel Brucellosis in Ethiopia: Seroprevalence and Associated Risk Factor

Oct 2023 DOI 10.14302/issn.2575-1212.jvhc-23-4532
Sultan Abda NejaCorresponding author

Camels are a significant source of income for nomadic populations in many developing countries, including Ethiopia. Camels are well adapted to dry and semi-dry regions, providing income, food security, and transportation. However, camel production and productivity are constrained by infectious disea…

RET 898-901Del mutant, a variant of unknown significance, has a durable response to Pralsetinib in a Medullary Thyroid Carcinoma patient

Sep 2023 DOI 10.14302/issn.2574-4496.jtc-23-4722
Patrick J. ConwayCorresponding author

Background Patients with distant metastatic Medullary Thyroid Carcinoma (MTC) have an estimated 40% ten-year survival rate. Gain of function mutations in the REarranged during Transfection or RET gene in MTC can result in an aggressive phenotype resistant to traditional therapy. In this case report,…

Low Seroprevalence of Brucella Spp. among Remote Colombian Communities from the Sierra Nevada De Santa Marta

Aug 2023 DOI 10.14302/issn.2641-9181.ijnr-23-4658
Regina OakleyCorresponding author

Brucella species cause a high burden of disease globally, infecting both humans and animals; however, One Health has been under-appreciated in Colombia. This study aimed to determine the seroprevalence of Brucella spp. in two remote indigenous communities from the Sierra Nevada de Santa Marta, Colom…

Research Gaps in Contaminants of Emerging Concern (CECs): Routes to the Standardization of Chemical Test Methods By GC/LC-Mass Spectrometry: A Review

Jun 2023 DOI 10.14302/issn.2377-2549.jndc-23-4615
Thavrin ManickumCorresponding author

A literature review was undertaken with a focus on 1) identifying the research gaps regarding CECs, 2) identifying the most common ones, and 3) identifying the typical analytical methods/technologies employed, for their analysis. A total of 214 papers were noted, with a total of 21 review articles (…

The trajectory of immunoglobulins immune response against the different amounts of xenobiotics matches the trajectory of biological changes associated with ageing: A systematic review

Mar 2023 DOI 10.14302/issn.2474-7785.jarh-22-4381
Yilkal Tariku BelayCorresponding author

Background Ageing is a life process in which progressive molecular, cellular, physiological and anatomical changes manifesting in humans and animals including other organisms lead to the decline of biological functions. Immunoglobulins (Igs) are glycoprotein molecules produced by white blood cells m…

Molecular Confirmation of Staphylococci Strain’s Identification Isolated in the Hospital and University Center of Brazzaville, Republic of Congo

Nov 2022 DOI 10.14302/issn.2690-4721.ijcm-22-4341
Léa Gwladys GangoueCorresponding author

Bacteria of the genus Staphylococcus are pathogenic Gram-positive bacteria responsible for various infections, including skin suppuration, which can be severe or chronic. The objective of this study was to confirm Staphylococci strain’s identification isolated by bacteriological methods from biologi…

Pandemic Impact on Population Structure

Oct 2022 DOI 10.14302/issn.2692-1537.ijcv-22-4319
Yurii V. EzepchukCorresponding author

The victims of the first wave of the pandemic caused by the coronavirus Covid-19 were tens of millions of people in the population inhabiting the Earth. A previously unknown strain of Covid 19, which has a specific affinity for lung tissue and high contagiousness, has demonstrated a global danger to…

A Review of Literature and Article on Importance of Nidan Panchak Ayurveda

Jul 2022 DOI 10.14302/issn.3070-3360.ijco-22-4231
Aman MulaniCorresponding author

Nidana Panchaka is one of Ayurveda's several diagnostic procedures. It is the most significant way for determining the source of an illness, as well as predicting its prognosis. Nidana Panchaka comprises of five items which are Nidana (etiological factors), Purvaroopa (primordial symptoms), Roopa (s…

Osteoarthritis and Neuromuscular Deficits: Can a Causative Role be Discounted- Key 2017-2022 Observations

May 2022 DOI 10.14302/issn.2474-7785.jarh-22-4191
Ray MarksCorresponding author

Background The origin of osteoarthritis, the most common disabling disorder of older adults remains uncertain. Aim This mini review examines the possible role played by various neuromuscular deficits in the osteoarthritis etiopathogenic process. Methods and Procedures Articles that haveaddressed the…

What is known Today about Nutrition and Microbiota

Mar 2022 DOI 10.14302/issn.2379-7835.ijn-22-4120
Paolo MainardiCorresponding author

We are experiencing years of profound cultural revolution. New insights into the microbiota upset concepts in physiology, medicine, and nutrition. The role of the microbiota for our health is increasingly evident. We are increasingly certain that our health depends on that of the microbiota, or, rat…

Content of Copper, Iron, Iodine, Rubidium, Strontium and Zinc in Thyroid Malignant Nodules and Thyroid Tissue adjacent to Nodules

Feb 2022 DOI 10.14302/issn.2689-5773.jcdp-22-4065
Vladimir ZaichickCorresponding author

Thyroid malignant nodules (TMNs) are the most common endocrine cancer. The etiology and pathogenesis of TMNs must be considered as multifactorial. Diagnostic evaluation of TMNs represents a challenge, since there are numerous benign and malignant thyroid disorders that need to be exactly attributed.…

Association of Serum Calcium Level with other Risk Factors of Ischaemic Stroke

Feb 2022
A K Al MirajCorresponding author

Introduction Calcium (Ca2+) plays an important role in the pathogenesis of ischemic cell damage. Intracellular Ca2+ accumulation leads to neuronal damage by triggering the cycle of cytotoxic events, however the relationship of serum Ca levels and the pathways involved in ischemic injury is unclear.…

RETRACTED: Postulation of the Effect of Unpredicted Predisposing Factors for Post-Tonsillectomy Bleeding

Aug 2021 DOI 10.14302/issn.2379-8572.joa-21-3913
Mohamed Bofares KhaledCorresponding author Professor of otorhinolaryngology Omar Almoukhtar University, Elbyda, Libya

This article has been retracted on 20 January 2022. VIEW THE RETRACTION NOTICE (https://doi.org/10.14302/issn.2379-8572.joa-25-5850) Back ground and Objectives Tonsillectomy is the most common surgical procedure in specialty of otorhinolaryngology. Therefore there are frequent premises regarding thi…

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