Search results for “toxicity”

About 52 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching toxicity — open any to read the full text, or download the PDF or XML.

Assessing the Effects of Blessing (Biofield) Energy Treatment on Zea mays L. saccharata Productivity

Sep 2026 DOI 10.14302/issn.2638-4469.japb-26-6431
Snehasis JanaCorresponding author

Background Sweet corn (Zea mays L. saccharata) is a high-demand, nutrient-sensitive cereal crops whose yield and crop quality depend heavily on early vegetative vigor and stress resilience. Spiritual Blessing (Biofield) Energy Treatment (SBET) has emerged as a non-invasive, biostimulatory approach t…

Lineage-Specific Disruption of Hematopoiesis by Oxaliplatin: Mechanisms of Erythropoietin Resistance and Immune Suppression

Feb 2026 DOI 10.14302/issn.2372-6601.jhor-25-5944
Mikhail Y. BerezinCorresponding author

Background Oxaliplatin, a widely used chemotherapeutic agent, is associated with hematologic toxicities such as anemia, leukopenia, and thrombocytopenia. Despite their clinical relevance, the molecular mechanisms underlying lineage-specific bone marrow suppression remain poorly understood. Methods W…

The Application of Immunoglobulins Immune Response in the Discovery and Development of Safe Therapeutic Agents: A Review Article

Jan 2024 DOI 10.14302/issn.2328-0182.japst-23-4771
Yilkal Tariku BelayCorresponding author

Background Immunoglobulins are bio-receptors found embedded in the cell membrane with a biological role that detects the harmful molecules of a test compound. These bio-receptors interface between a biological system and its external environment that transduce information to the effector via interme…

Research Gaps in Contaminants of Emerging Concern (CECs): Routes to the Standardization of Chemical Test Methods By GC/LC-Mass Spectrometry: A Review

Jun 2023 DOI 10.14302/issn.2377-2549.jndc-23-4615
Thavrin ManickumCorresponding author

A literature review was undertaken with a focus on 1) identifying the research gaps regarding CECs, 2) identifying the most common ones, and 3) identifying the typical analytical methods/technologies employed, for their analysis. A total of 214 papers were noted, with a total of 21 review articles (…

Ozone/Oxygen Molecules Exert Mild Oxidative Stress on Testis Mitochondria Isolated from the Rat Testicular Ischemia/Reperfusion Injury

Jun 2022 DOI 10.14302/issn.2471-2140.jaa-21-3911
Morteza IzadiCorresponding author

Testicular ischemia-reperfusion injury is an urgent situation which needs a timely and precise diagnosis for prevention of testis damages. Here in we investigated ozone/oxygen therapy in Testicular Ischemia/Reperfusion Injury. For this purpose, animals (rats) were divided to four groups; control, to…

BaMtox, a Myotoxic Enzyme Isolated from the Venom of the Bothrops Alternatus

Mar 2022 DOI 10.14302/issn.2832-4048.jsm-21-3986
Luiz Fernando Moreira IzidoroCorresponding author

Snake envenomations are responsible for a high percentage of deaths, as these toxic proteins induce severe local and systemic effects. In Brazil, the Bothrops genus is responsible for a satisfactory fraction of accidents, including Bothropsalternatus, recognized as urutu, whose venom is capable of i…

Attenuation of Microcystins Using Electron Beams and Gamma Radiation: A Study with Environment-Bound Conditions

Oct 2021 DOI 10.14302/issn.2641-7669.ject-21-3970
Joao Dias Toledo Arruda-NetoCorresponding author

Microcystins (MCs) are toxins profusely synthesized by cyanobacteria, causing livestock poisonings and endangering human health. We design and execute an experiment to investigate the attenuation (degradation) of microcystins by exposing them to gamma radiation and electron beams at doses of 0 (cont…

The Use of Metabolomic Tool in Assessing Environmental Exposure

Oct 2021 DOI 10.14302/issn.2690-0904.ijoe-21-3966
Michele Polyana Rocha MendesCorresponding author

The impact of the environment on the development of non-communicable chronic diseases has gained prominence in recent years. In this context, a new chemical exposure assessment strategy is needed that is capable of revealing multiple exposures, as well as reflecting the cumulative interaction betwee…

Antioxidative Protective Effect of Ozone Therapy on Isolated Mitochondria from Human Sperm

Aug 2021 DOI 10.14302/issn.2471-2140.jaa-21-3910
Morteza IzadiCorresponding author

Oxidative stress is implicated in male infertility and significantly higher reactive oxygen Species (ROS) are detected in 25% of infertile males. We showed that Ozone oxygen therapy (O2/O3) induces protective effects for oxidative stress factors and its consequences on isolated mitochondria obtained…

Comparative Survival Assessment of Two-Dimension (2D) vs Three-Dimension (3D) Brachytherapy Treatment in Cervical Cancer: A Retrospective Case Control Study

Nov 2020 DOI 10.14302/issn.2766-8630.jrnm-20-3594
Pitchaya SakyanunCorresponding author

Purpose The purpose of this study was to assess the efficacy (overall survival, local control, progression free survival (PFS) and toxicities between two dimension (2D) and three dimension (3D) CT guided brachytherapy without using interstitial needles in cervical cancer patients. Material and Metho…

NNC55-0396 Reduces SH-SY5Y Cell Damage Induced by Bupivacaine Hydrochloride

Aug 2020 DOI 10.14302/issn.2641-7669.ject-20-3529
Xianjie WenCorresponding author

Background Local anesthetic neurotoxicity is a common complication in clinical anesthesia, which can cause permanent nerve damage in severe cases. The T-type calcium channel is an important channel for regulating the excitability of neurons. Normally, extracellular calcium ions enter the cell throug…

Evaluation of Biological Activities of Opuntia Ficus Indica Cladodes Extract Against Cadmium-Induced Osteoporosis in Male Wistar Rats

Aug 2020 DOI 10.14302/issn.2328-0182.japst-20-3447
Jihen TalebCorresponding author

The cactus Opuntia ficus indica (L.) Mill. (Cactaceae) is widely used in Tunisian medicine for the treatment of various illnesses. The purpose of the present study was to investigate the antioxidant activities of cactus cladode extract (CCE) and to assess the protective effects of Opuntia ficus indi…

Biomedical Infophysical Models of Filtering Ghost Airflows by Wearing Masks and Maintaining Social Distancing to Prevent COVID-19 and Reopen All Systems after Shutdowns (Lockdowns)

Jun 2020 DOI 10.14302/issn.2641-4538.jphi-20-3426
Kang ChengCorresponding author

The COVID-19 pandemic has killed more than 400 thousand and infected more than 7 million people in the whole world as of 06/10/2020. Many open systems, such as educations, transportations, entertainments, sports or foods, have been completely or partially locked down in many regions of the world to…

Effect of Hexavalent Chromium on the WBCs of the Fresh Water Fish, Labeo rohita

May 2020 DOI 10.14302/issn.2641-7669.ject-20-3313
A.J ThatheyusCorresponding author PG & Research Department of Zoology, The American College, Madurai, Tamil Nadu, India.

Industrial effluents containing heavy metals may reach aquatic systems either through direct discharge or surface runoff and cause damage to aquatic organisms affecting their immune system and health. Hence the present study has been undertaken to observe the effects of hexavalent chromium on the WB…

Impact if Chlorpyrifos on the Second Instar Mosquito Larvae as Bioindicator in El-Beheira Governorate, Egypt

Mar 2020 DOI 10.14302/issn.2691-3208.ijli-20-3268
EH RadwanCorresponding author

Pesticides are the major source of concern as water pollutants. Chlorpyrifos (CPY) (O,O-diethyl-O-(3,5,6-trichloro-2-pyridinyl) phosphorothioate; CAS No. 2921-88-2). CPY is a widely used organophosphate insecticide. The aim of current study was to determine the effects of CPY on the second instar la…

Nucleoside and Nucleotide Reverse Transcriptase Inhibitors Induce Aging by Inhibiting Telomerase Function

Nov 2019 DOI 10.14302/issn.2324-7339.jcrhap-19-3070
Bechan SharmaCorresponding author

The telomeres existing at the end of the eukaryotic chromosome, play an important role in localization, pairing of homologous chromosomes during cell division and synapsis formation, while telomerase is involved in maintenance of the telomere length. The application of antiHIV-1 molecules particular…

Trigonella Foenum Graecum Extract Benefits on Hematological, Biochemical and Male Reproductive System as a Complementary Therapy with Glimepiride in Treating Streptozotocin Induced Diabetic Rats

Feb 2019 DOI 10.14302/issn.2374-9431.jbd-19-2613
Eman H. RadwanCorresponding author

Diabetes mellitus (DM) is a chronic metabolic disorder. Streptozotocin is a naturally occurring cytotoxic chemical, particularly toxic to the pancreas and insulin producing beta cells in mammals and induces diabetes. Glimepiride is a second generation sulfonylurea, used as second-line or add-on trea…

Ecotoxicological Assessment of Leachate from Municipal Solid Waste Dumpsites

Jan 2019 DOI 10.14302/issn.2641-7669.ject-18-2550
Tariwari C. N AngayeCorresponding author

The ecotoxicological effects of leachates from dumpsite have become a major problem. Leachates arising from waste dumpsites are transported by surface runoff or infiltration through the soil and become bioavailable in the ecosystem. The ecotoxicological assessment of leachates from 6 dumpsite in Yen…

Effect of Bone Marrow and Adipose Mesenchymal Stem Cells on Rat Intestinal Injury Induced by Methotrexate

Nov 2018 DOI 10.14302/issn.2640-6403.jtrr-18-2449
Ebtehal Mohammad FCorresponding author

Methotrexate (MTX) is an anti-metabolite in cancer chemotherapy and is associated with various toxicities assigned to inflammation and oxidative stress. The present study was undertaken to corroborate the therapeutic effects of bone marrow mesenchymal stem cells (BM-MSCs) and adipose-derived mesench…

Medicinal Plants and their Traditional Uses

Oct 2018 DOI 10.14302/issn.2638-4469.japb-18-2423
Cumali KeskinCorresponding author

This review surveys medicinal plants and their traditional uses, summarizing common indications and bioactive constituents. It contrasts perceived safety with evidence on efficacy and potential toxicity or interactions. The authors highlight the need for standardized preparations and controlled stud…

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