Search results for “uncommon”

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21 articles
All Journal of Otolaryngolog… 3 Journal of Ophthalmic Sc… 2 Journal of Sports and Ex… 2 Journal of Body Fluids 1 Journal of Clinical Case… 1 Journal of Hypertension… 1 Journal of Pediatric Hea… 1 Journal of Diseases 1 Journal of Hematology an… 1 Journal of Public Health… 1 Journal of Spleen and Li… 1 Journal of Women's Repro… 1
Journal of Cancer Genetics and Biomarkers Open Access

Correlation of Oncotype DX Recurrence Score with the Expression of Insulin Receptor Substrate Proteins in Estrogen Receptor + Breast Cancer

May 2014 DOI 10.14302/issn.2572-3030.jcgb-13-369
Ashraf KhanCorresponding author

Insulin receptor substrate (IRS) 1 and 2 are downstream signaling proteins that influence breast pathophysiology. IRS-1 promotes carcinoma cell proliferation; whereas IRS-2 regulates cell motility, invasion, and glycolysis. Our lab has shown that distinct cellular localization of IRS-2 also plays a…

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