Search results for “Approach”

Maxillary Constriction with Skeletal Class II Malocclusion - A Comprehensive Treatment Approach.

This case report reiterates the fact that a bilateral posterior crossbite with severe skeletal class II malocclusion in the growth period could be effectively treated by a comprehensive approach with a rapid palatal expansion appliance followed by fixed appliance therapy. A 14-year-old boy presented…

Exploring the use of an iPhone App: A Novel Approach to Dietary Assessment

Recent advancements in smartphone technology have provided new methods of dietary assessment. An iTunes application (app) called Meal Snap lets users take pictures of the meal they eat, and then estimates the calories of the food items eaten. We conducted a pilot study to explore the user-friendline…

A Multidisciplinary Approach in The Diagnosis of Allergic and Non-Allergic Respiratory Diseases: Nasal Cytology and Feno.

Upper and lower airway disease is a common condition. Its prevalence is increasing in different areas of the world, but, at present, non-allergic rhinitis is underestimated. The aim of this study was to investigate FeNO (fractional exhaled nitric oxide) and nasal cytology in allergic and non-allergi…

MicroRNA Profiling of Differentiated, Poorly Differentiated and Anaplastic Thyroid Carcinoma, a Comparative Approach

Thyroid carcinomas encompass a wide spectrum ranging from differentiated thyroid carcinoma (DTC) to poorly differentiated (PDC) and anaplastic thyroid carcinoma (ATC). DTC of both follicular (FTC) and papillary (PTC) types can progress to PDC and AC. The aim of our study was to evaluate if there is…

Targeting Cell Metabolism in Chronic Lymphocytic Leukaemia (CLL); Aviable Therapeutic Approach?

Targeting cell metabolism is a therapeutic approach which has been used for the treatment of cancers with high levels of proliferation. Inhibition of metabolic processes in cancer cells has shown synergy with current therapeutic options to reduce refractory disease and relapse. In contrast, chronic…

Evaluation of Recruitment Approaches for the HPTN 052 Clinical Trial of HIV Serodiscordant Couples in Rural Western Kenya

Recruitment of couples is important for study success. The multi-centered HPTN 052 clinical trial was designed to evaluate whether immediate versus delayed use of ART by HIV-infected individuals would reduce transmission of HIV to their HIV-uninfected partners. The objective of this study was to ret…

RETRACTED: Calculating the Number of Rigling on Highly Deformed Bullets: A Digital Measurement and Mathematical Formula Approach

Carbapenem-resistant Enterobacterales at a quaternary public hospital in Durban, KwaZulu-Natal: Ascertaining the clinical and molecular paradigm shift following COVID-19

Background Extensive carbapenem use has resulted in an increasing occurrence of difficult-to-treat resistant gram-negative bacteria (DTR-GNB), such as carbapenem-resistant Enterobacterales (CREs). The international antimicrobial resistance (AMR) landscape was profoundly impacted due to varying antib…

Advancements in Cancer Gene Therapy: A Comprehensive Review

Gene therapy is a cancer treatment that is superior to chemotherapy, radiotherapy, and other less selective and specifically harmful forms of treatment. It entails the aberrant replacement, alteration, and deletion of a gene within a normal or healthy copy of a gene. Recent trials have made signific…

The Advantages of Employing the Immune Response Mediated by Immunoglobulins in Preclinical and Clinical Research: An Essential Review

Immunoglobulins, commonly known as antibodies, are glycoprotein molecules present on B lymphocytes and within the bloodstream. They are essential components of the immune response, as they detect the harmful molecules of test compounds and stimulate the immune system to manifest proportional counter…

Assessing the Effects of Blessing (Biofield) Energy Treatment on Zea mays L. saccharata Productivity

Background Sweet corn (Zea mays L. saccharata) is a high-demand, nutrient-sensitive cereal crops whose yield and crop quality depend heavily on early vegetative vigor and stress resilience. Spiritual Blessing (Biofield) Energy Treatment (SBET) has emerged as a non-invasive, biostimulatory approach t…

Partial Substitution of Mineral Fertilizers with Organic Fertilizers to Increase Yield and Profitability of Irrigated Lowland Rice Cultivation

Uganda has the world's lowest fertilizer use rate at just 1-1.5 kg per hectare. This limited use is a key factor hindering rice productivity in the country. Farmers can use affordable organic fertilizers to partially replace expensive mineral fertilizers, increasing the profitability of rice cultiva…

Chemoenzymatic Synthesis of Purine Modified 3′-deoxy-D-ribonucleosides and Evaluation of Their Antiproliferative Activity

Chemoenzymatic synthesis of a series of purine modified 3′ deoxyribonucleosides was studied from purine derivatives as acceptors and an excess of 3′-deoxyuridine as the donor, prepared by the chemical deamination of 3′-deoxycytidine, using recombinant uridine and purine nucleoside phosphorylases as…

A Unifying Theory of Alzheimer’s and Other Neurodegenerative Diseases

Background/Objectives The etiology and pathophysiology of neurodegenerative diseases are incompletely understood, and the treatments largely ineffective. A unifying theory that explains otherwise poorly understood observations may help to enhance therapeutic outcomes. Methods Here is proposed a unif…

Contributory Factors to Malnutrition in Children under Five Years Received in Consultation at the Pediatric Service of Saint Martin of Papane Hospital in Northeast Benin

Malnutrition is a major global public health issue, especially in low-income regions. Identifying contributing factors is crucial for effective interventions. This study aims to determine the factors contributing to malnutrition among children under 5 years old at Papané Hospital in northeast Benin…

A Framework for Achieving an Adequate and Effective Health Care System Through Primary Care in Grenada: A Systematic Review

With an emphasis on the implications for Grenada, this systematic study delves into the complexities of setting up a successful primary healthcare system in tiny island states. It is emphasized how crucial primary healthcare is as a community-based, preventative paradigm and how it improves general…

Herpes Zoster Ophthalmicus Presenting with Suspected Orbital Myositis Following Recent Recombinant Zoster Vaccination

Herpes zoster ophthalmicus (HZO) is a manifestation of varicella-zoster virus (VZV) reactivation involving the ophthalmic division of the trigeminal nerve, carrying significant risk of vision-threatening complications. Diplopia in HZO is often attributed to cranial nerve palsy, although orbital myos…

Random Forest Classifier for Respiratory Mortality Analytics

Respiratory diseases remain a major contributor to hospital morbidity and mortality worldwide, particularly among elderly patients and individuals with severe pulmonary compromise. Accurate prediction of respiratory mortality is clinically important for triage, resource allocation, ICU utilization,…

Implementing Evidence-Based Occupational Therapy for Multiple Sclerosis Rehabilitation: Exploring Knowledge on Barriers, Facilitators and Strategies

Background A persistent gap remains between evidence-based health care and its application in routine practice. This challenge is particularly prominent in allied health professions like occupational therapy (OT), where interventions are complex, individualized and centred on patients' daily functio…

Secondary Hip Fractures among Aging Adults with a Previous Hip Fracture History: Cumulative 50 Year Overview, Analysis, and Possible Antidote as Observed from 1974-2026 Data Sources

Hip fractures, which remain an immense public health concern, have been subject to study and prevention efforts for many decades, but with limited success in averting either incident, second or subsequent hip fractures, commonly attributed to a combination of age related proclivity to fall, low bone…