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May 2022 DOI 10.14302/issn.2379-7835.ijn-22-4170
Magnus Michael Chukwudike AnyakudoCorresponding author
Garden egg nutritional values are numerous. However, few nutritional and epidemiological data exist on the impacts of garden egg consumption on diabetes control. In this experimentally-control designed nutritional study, the effects of scarlet garden egg species (Solanum aethiopicum L.) on lipoglyce…
Mar 2022 DOI 10.14302/issn.2638-4469.japb-22-4102
O.D. AbuCorresponding author
The safety of plant-derived bioactive compounds has become a global concern. The present study investigated the dose response of total saponins isolated from the stem bark of Dialiumguineense. Adultmale Wistar rats (n = 15) weighing 170 – 190 g (mean weight = 180 ± 10 g) were randomly assigned to th…
Apr 2021 DOI 10.14302/issn.2328-0182.japst-21-3778
Okiemute Rosa Johnson-AjinwoCorresponding author
Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Port Harcourt, Nigeria.
This study aims at investigating the antipyretic activity of different solvent fractions of the root bark of Rutideaparviflora(Rubiaceae). This plant is used ethno-botanically by the people of Ethiope East-West Local Government Area of Delta State, Nigeria to treat various ailments such as inflammat…
Apr 2020 DOI 10.14302/issn.3070-2313.jeh-20-3270
Linus Anderson EnyeCorresponding author
Department of Anatomy, College of Medicine and Health Sciences, Afe Babalola University Ado Ekiti
Plants have played a significant role in maintaining human health and improving the quality of human life. Therefore, this present study seeks to evaluate the role of its alkaloid fraction in the hypothalamic-pituitary-testicular axis after dichlorvos poisoning in mice. A total of 25 male mice, weig…
Mar 2020 DOI 10.14302/issn.2379-7835.ijn-20-3175
Cyril Abang AgborCorresponding author
Department of Anatomy, Collage of Basic Medical Sciences, University of Calabar, Nigeria
Local Nigerian men have been using AuriculariaPolytricha as a treatment for sexual dysfunction without supporting evidence from scientific experiments. This study was to investigate the effect of ethanolic extract of A. Polytricha on testicular DNA expression and some oxidative stress markers using…
Mar 2020 DOI 10.14302/issn.2577-2279.ijha-20-3215
O. Atinuke AnjorinCorresponding author
Department of Anatomy and Cell Biology
Since oxidative stress impairs the cardiovascular function, the hypothesis from the present study is that the treatment of paraquat-exposed adult Wistar rats with methanolic extract of Abelmoschus esculentusseed would reduce paraquat-induced cardiovascular damage. Thirty healthy female Wistar rats w…
Jan 2020 DOI 10.14302/issn.2474-9273.jbtm-19-3157
Snehasis JanaCorresponding author
Sleep biomarkers in brain such as melatonin, BDNF (Brain-derived neurotrophic factor), PGD2 (Prostaglandin D2), leptin, orexin-A, and acetylcholine were evaluated in the unpredictable chronic stress (UCS) rodent model in the presence of Consciousness Energy Healing Treated (the Trivedi Effect®) nove…
Dec 2019 DOI 10.14302/issn.2577-2279.ijha-19-3110
N.A. KiryanovCorresponding author
Izhevsk State Medical Academy, Izhevsk, Russia
Aim To study the chondroplasty efficacy of the bone matrix obtained using an original technology in restoring cartilage defect of the knee joint. Material and Methods Marginal defects were modeled on the surface of the distal end of the femur in 40 adult male Wistar rats. The bone matrix obtained us…
Mar 2019
Valeria Paula Sassoli FazanCorresponding author
We used a behavioral test to investigate long-term consequences of neonatal noxious stimulus in the anxiety-like behavior and describe differences between males and females. Male and female Wistar rats were submitted to either tactile (control groups) or noxious stimulus (pain groups) since birth, f…
Dec 2018 DOI 10.14302/issn.2578-8590.ipj-18-2524
Francesco CrespiCorresponding author
The pineal gland constitutes a major neuroendocrine organ in the brain. By mean of its neurohormone melatonin it transduces exogenous signals such as circadian and seasonal variations of light and temperature into proper hormonal changes which adjust and adapt internal endocrine functions. Alteratio…
Nov 2018 DOI 10.14302/issn.2640-6403.jtrr-18-2449
Ebtehal Mohammad FCorresponding author
Methotrexate (MTX) is an anti-metabolite in cancer chemotherapy and is associated with various toxicities assigned to inflammation and oxidative stress. The present study was undertaken to corroborate the therapeutic effects of bone marrow mesenchymal stem cells (BM-MSCs) and adipose-derived mesench…
Oct 2018 DOI 10.14302/issn.2328-0182.japst-18-2341
Nyemb NyunaїCorresponding author
The present investigation was carried out to evaluate the safety of a stem bark aqueous extract of Harunganamadagascariensis Lam. (Hypericaceae) by determining its potential toxicity after acute and subacute administration in rodents. Acute toxicity tests were carried out in mice and the behavior, d…
Aug 2018 DOI 10.14302/issn.2640-6403.jtrr-18-2158
Yu.M. IrianovCorresponding author
Purpose of Study: To study reparative osteogenesis and tissue integration characteristics for implanting three-dimensional mesh structures of titanium nickelide into a bone cavitary defect. Material and Methods: The authors modeled cavitary defects of femoral metaphysis experimentally in Wistar rats…
Apr 2018 DOI 10.14302/issn.2577-2279.ijha-18-2030
N. A. KiryanovCorresponding author
Introduction: The use of non-medicinal facilities for correcting processes in various pathological conditions is one of the most urgent problems of modern medicine. Purpose of the Work: To study the effect of low-intensity infrared laser radiation on reparative bone formation and angiogenesis in bon…
Feb 2018 DOI 10.14302/issn.2577-2279.ijha-18-1918
Kiryanov N.A.Corresponding author
Izhevsk State Medical Academy, Russia
This article has been retracted on August 03, 2026. VIEW THE RETRACTION NOTICE (https://doi.org/10.14302/issn.2577-2279.ijha-26-6430) Purpose of Study To study reparative osteogenesis and tissue integration characteristics for implanting three-dimensional mesh structures of titanium nickelide into a…
Dec 2017 DOI 10.14302/issn.2641-7669.ject-17-1789
M.E.Abdel-Salam OmarCorresponding author
Departments of Toxicology and Narcotics
We aimed to study the effect of buspirone, an anxiolytic drug and 5-HT1A agonist on liver injury induced by carbon tetrachloride (CCl4) in rats. Rats were orally treated with CCl4 (2.8 mL/kg in olive oil) along with buspirone at 10, 20 or 30 mg/kg once daily starting with CCl4 and for one week there…
Aug 2017 DOI 10.14302/issn.2688-5328.ijp-17-1600
Hristina ZlatanovaCorresponding author
The objective of our study was to evaluate the analgesic and anti-inflammatory activity, as well as possible organ toxicity of 2-3-3-methyl-pentanoic acid (compound 3d), a newly synthesized pyrrolic derivative, structurally similar to Celecoxib. Antinociception was assessed using animal pain models…
Jul 2017 DOI 10.14302/issn.2471-2140.jaa-17-1630
Aholia Jean- Baptiste AdépoCorresponding author
Laboratoire de Toxicologie et Hygiène Agro-industrielle, UFR Sciences Pharmaceutiques et Biologiques, Université Félix Houphouët-Boigny, BP V 34, Abidjan, Côte d’Ivoire
Introduction: Aflatoxins are cytotoxic andserve as one of the key risk factors of hepatocellular carcinoma. Currently, plants and extract are widely used as potential scavenging substances for the detoxification of mycotoxins. Thus, this study aims to investigate the activity of the crude ethanolic…
May 2017 DOI 10.14302/issn.2470-0436.jos-17-1453
Jie ZhangCorresponding author
Purpose: High intraocular pressure (IOP) is known to result in retinal ganglion cell (RGC) loss, both with chronically raised intraocular pressure (such as with glaucoma) and with acute raises in pressure (due to injury or acute angle closure). Because IOP is often raised during ocular surgery, the…
Mar 2017 DOI 10.14302/issn.2572-5424.jgm-16-1352
Syed Qaiser ShahCorresponding author
In this investigation, Rifabutin dithiocarbamate (RFND) was labeled with Technetium-99m (99mTc) using tricarbonyl technique. The labeled RFND was further characterized in terms of radiochemical purity, stability in saline & serum, in vitro bacterial binding, biodistribution in animal model rats and…