Search results for “disease”

About 100 results in articles

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A Summary of Circular RNAs in Alzheimer's Disease

Jan 2021 DOI 10.14302/issn.2470-5020.jnrt-20-3619
Keping ChenCorresponding author

Circular RNAs (circRNAs) are recently rediscovered eukaryotic molecules that form a covalently closed-loop structure through a special type of alternative splicing known as backsplicing. These closed-loop structures are highly stable and resistant to RNase degradation, and are thereby expressed in a…

Rare Association Between Neuroimmunological Diseases: A Possible Autoimmune Polyglandular Syndrome Type IV

Jun 2020 DOI 10.14302/issn.2641-5518.jcci-20-3370
Marcus Vinícius Magno GonçalvesCorresponding author

Autoimmune polyglandular syndromes (APS) are a diverse group of clinical conditions characterized by loss of immune tolerance in various tissues. This condition can be diagnosed in childhood or adulthood, with changes in the components of the disease throughout life. Here, an unusual case of associa…

Molecular Study of Hepcidin HAMP (-582A/G) Gene Polymorphisms and Measurement of Serum Hepcidin Level among Sudanese Patients with Anemia of Chronic Kidney Disease

May 2020 DOI 10.14302/issn.2575-7881.jdrr-20-3343
Amged Hussen AbdelrhmanCorresponding author

Background Anemia of chronic disease is anemia found in certain chronic disease states, is typically marked by the disturbance of iron homeostasis or hypoferremia. Chronic renal failure is currently known as Chronic Kidney Disease (CKD) or Chronic Renal Insufficiency (CRI) implies long-standing, pro…

Care in Chronic Diseases and in "Frail" Patients in General Practice

May 2020 DOI 10.14302/issn.2692-5257.ijgp-20-3375
Lucio MangoCorresponding author

The world of chronicity is an area in progressive growth that involves a considerable commitment of resources, requiring continuity of assistance for long periods of time and a strong integration of health services with social ones and those requiring residential and territorial services often not s…

Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges in Toxicology Practice

Apr 2020 DOI 10.14302/issn.2691-8862.jvat-20-3314
Shimaa M. MotaweiCorresponding author

This article reviews toxicology practice challenges during COVID‑19, including laboratory safety, chemical exposures, therapeutics, and public health messaging. It identifies research needs and operational adaptations to support preparedness for future events.

Medical Concepts with Clinical-Epidemiological Implications that have to be Re-Assessed Since the Coronavirus Disease 2019 (Covid-19) Pandemic

Apr 2020 DOI 10.14302/issn.2692-5257.ijgp-20-3299
Jose Luis TurabianCorresponding author

The coronavirus disease 2019 (COVID-19) pandemic is something new that baffles us. The dominant health model and the theory that supported it until before COVID-19 are refuted or invalidated by observing the current tragically situation, which also implies lasting changes in that new medical model.…

Association of BsmI and ApaI Polymorphisms of the Vitamin D Receptor Gene with Dyslipidemia in Patients with Coronary Artery Disease.

Mar 2020 DOI 10.14302/issn.2374-9431.jbd-20-3195
E.G SergeevaCorresponding author FIRST St. Petersburg state medical University named after academician I. P. Pavlov

Purpose The goals of the present study were to assess the genotypic and allelic distribution of Bsm-I (rs1544410) and Apa-I (rs7975232) polymorphisms of the vitamin D receptor (VDR) gene in coronary artery disease (CAD) patients in comparison to control patients of the same age without CAD and to de…

Urgent Prevention of Corona Virus Disease 2019 (COVID-19): Chinese Eating and Mask-Wearing Cultures

Mar 2020 DOI 10.14302/issn.2641-4538.jphi-20-3264
Kang ChengCorresponding author

Chinese people have a very good mask-wearing culture; it is normal to wear masks to protect their faces from wind and pollution. Thus, they easily accept the wearing of masks to prevent infectious diseases, as seen with the Corona Virus Disease 2019 (COVID-19) in China today. However, Chinese people…

A Review The use of Cerebrolysin in Pediatric Charcot Marie Tooth Disease

Feb 2020 DOI 10.14302/issn.2470-5020.jnrt-20-3226
Aamir Jalal Al MosawiCorresponding author

Charcot Marie Tooth disease is a is a very chronic progressive hereditarymotor and sensory neuropathy characterized by progressive weakness andloss of touch sensation across various parts of the body. There are no curative or effective medical therapies that can ameliorate the disability associated…

Sustained Clinical Response of Pseudotumoral Lesion of the Central Nervous System in Behcet's Disease After Treatment with Infliximab. Case Report.

Feb 2020 DOI 10.14302/issn.2641-5518.jcci-20-3166
Joseph Bruno Bidin BrooksCorresponding author

This case documents a pseudotumoral CNS lesion in Behcet's disease with sustained response to infliximab therapy. Clinical evolution, neuroimaging changes, and rationale for TNF‑alpha inhibition are detailed. The report supports considering biologic therapy for refractory neuro‑Behcet manifestations…

Implementation of an Elemental Diet in Five Children Diagnosed with Autism Spectrum Disorder Presenting with Gastrointestinal Disease: A Brief Report

Feb 2020 DOI 10.14302/issn.2379-7835.ijn-20-3181
Kelly BarnhillCorresponding author

Autism Spectrum Disorder (ASD) is a developmental disorder characterized by impaired communication and social interaction. Children with ASD are frequently diagnosed with gastrointestinal (GI) issues, including inflammatory bowel disease (IBD), gastroesophageal reflux, abdominal pain, diarrhea, and…

Nutritional Care for Patients with Ebola Virus Disease in Ebola Treatment Units – Past and Current Experiences from Practitioners

Nov 2019 DOI 10.14302/issn.2379-7835.ijn-19-3083
Mija VerversCorresponding author

Background In November 2014, the World health Organization (WHO), in collaboration with United Nations Children's Fund (UNICEF), and the World Food Programme, produced interim guidelines (iGL) on providing nutritional support to patients in Ebola treatment units (ETUs). They have been translated int…

Capsaicin: A Potential Therapy Adjuvant for Intestinal Bowel Disease

Nov 2019 DOI 10.14302/issn.2574-4526.jddd-19-3063
Jacqueline I Alvarez-LeiteCorresponding author

Most of the patients with inflammatory bowel disease avoid pepper or spicy food, alleging that this condiment causes anal sensation of burning and accelerates intestinal movements. Capsaicin is the main bioactive component of peppers responsible for the pungent flavor that characterizes red peppers.…

Comparison of Dipper and Non-Dipper Hypertension Patterns According to Chronic Kidney Disease Stage

Sep 2019 DOI 10.14302/issn.2574-4488.jna-19-3008
Zeki AydinCorresponding author

Introduction Hypertension is a major cardiovascular risk factor. There is a strong relationship between blood pressure (BP) elevation and stroke, myocardial infarction, heart failure and mortality due to kidney disease. It is known that the loss of the dipping pattern in hypertension is associated w…

Severe Infantile Blount’s Disease in Kumasi, Ghana: A Case Report

Sep 2019 DOI 10.14302/issn.2474-3585.jpmc-19-3009
Dominic Konadu-YeboahCorresponding author

Blount’s disease, also known as tibia vara, is a developmental disorder involving the posteromedial proximal tibial physis resulting in progressive varus, procurvatum and internal torsion of the affected tibia 1. The condition was first published by Blount in 1973 2. The aetiology of this disease is…

Rosenthal's Disease (Hemophilia C or factor XI Deficiency) Revealed by Chronic Epistaxis: The First Observation in Sub-Saharan Africa.

Aug 2019 DOI 10.14302/issn.2372-6601.jhor-19-2982
Essohana PadaroCorresponding author

Objective Rosenthal's disease (RD) is a rare constitutional hemorrhagic disorder defined by factor XI deficiency. It is clinically characterized by the presence of minimal haemorrhage. We report the first observation of RD in Togo. Observation Mrs. G. A., 45 years old with no particular pathological…

Success for Big Infectious Disease Reimbursement Policy in China

Jul 2019 DOI 10.14302/issn.2641-4538.jphi-19-2966
Kun-xi NieCorresponding author

Big infectious diseases do harm to the whole society and it is highly crucial to control them on time. China has successful experience of launching reimbursement policy to control big infectious diseases, Severe Acute Respiratory Syndromes (SARS), efficiently. By evolution model, this article illust…

L162v Polymorphism of Par-Α Gene, A603g Polymorphism of Tissue Factor Gene and Risk of Coronary Heart Disease in Russian Population

Jun 2019 DOI 10.14302/issn.2374-9431.jbd-19-2788
E.G. SergeevaCorresponding author

Purpose The goal of this study is to determine the association of L162V polymorphism of PPAR-alpha gene, A603G polymorphism of tissue factor gene and the risk of coronary heart disease development in Russian population.   Materials and Methods A clinical and genetic study of 414 patients with CHD an…

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