Search results for “Dose”

About 99 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Dose — open any to read the full text, or download the PDF or XML.

Ultraviolet B Phototherapy Intervention in Patients with Multiple Sclerosis: A Prospective, Randomized Pilot Trial

Aug 2019 DOI 10.14302/issn.2470-5020.jnrt-19-2797
Catherine A Best-PopescuCorresponding author

Background There is substantial evidence, from well-conducted epidemiological studies, that low vitamin D levels are correlated with increased risk for MS, and multiple case control studies have implicated the involvement of vitamin D deficiency in MS etiology. Narrow-band Ultraviolet B (NB-UVB; 300…

Selective Cytotoxicity of Damsin Derivatives in Breast Cancer Cells

Apr 2019 DOI 10.14302/issn.2328-0182.japst-19-2759
Olov SternerCorresponding author

Cancer is the leading cause of death worldwide, and there is a constant need for new treatment strategies. Sesquiterpene lactones containing a 3-methylenedihydrofuran-2(3H)-one (or α-methylene-γ-lactone) moiety, for example damsin (1), are Michael acceptors that affect biological processes such as c…

Rice Yield Advances Under Precision Agriculture: a Farm Lesson

Mar 2019 DOI 10.14302/issn.2639-3166.jar-19-2691
Giorgio MasoeroCorresponding author

In precision agriculture (PA) fertilizing, based on soil testing, production maps and crop nitrogen (N) demand, is the key to maximizing yields and tempering fertilizer costs. A trend study has considered the output / input relationships performed on a farm that has progressively adapted to PA proce…

Chest Wall Prostheses for Pectus Excavatum and Poland Syndrome Using 3D-Printed Models: Technique and Outcomes After 25 Years' Experience

Feb 2019
Dallan P DarganCorresponding author

Background: Chest wall deformities may be managed with skeletal manipulation, which risks life-threatening complications. Custom-made prostheses are a less invasive surgical option, manufactured from silicone elastomer using 3D computed tomographic reconstruction and 3D-printed thoracic models. Meth…

Effect of Neosaxitoxin on Epidural Anesthesia in Cats: a Promising Alternative to Conventional Anesthetics

Feb 2019 DOI 10.14302/issn.2578-8590.ipj-19-2623
Jaime HinzpeterCorresponding author

Neosaxitoxin (NeoSTX) is a specific high-affinity inhibitor of voltage-dependent sodium channels, which has shown excellent results as a local anesthetic in various pathologies and post-operative protocols, since it effect is long-lasting and have virtually no side effects.The aim of this study was…

The Effects of Zanzalacht on the Gonotrophic cycle of the Adult House fly Musca Domestica

Feb 2019 DOI 10.14302/issn.2637-6075.jpae-19-2586
E H RadwanCorresponding author Zoology department, Faculty of Science, Damanhour University, Egypt.

Melia azedarach extract were applied by feeding the adult female flies on diets mixed with the extracts at different doses. The concentrations of Melia azedarach utilized were 1.8, 2.4 and 3.6%. The gonotrophic cycles of length of 90, 753, 67.6 and 84, 72, 68 hours were obtained after feeding at age…

Brain Hemodynamics and Cerebrovascular Reactivity in Patients with Tension-Type Headache

Jan 2019 DOI 10.14302/issn.2470-5020.jnrt-18-2555
Rizvan Ya. AbdullaievCorresponding author

Introduction: Tension-type headache (TTH) is very common, with a lifetime prevalence in the general population ranging in different studies between 30% and 78%. TTH, divided into episodic and chronic types, introduced in the manual "International Classification of Headache Disorders"(ICHD-I), is of…

Efficacy of DHA and EPA on Serum Triglyceride Levels of Healthy Participants: Systematic Review

Jan 2019 DOI 10.14302/issn.2379-7835.ijn-18-2469
Yohei KawasakiCorresponding author

Background Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are categorized as omega-3 poly unsaturated fatty acids (PUFAs) that are present in fish oil, etc. DHA and EPA omega-3 PUFAs have a well-established fasting serum triglycerides (TG) lowering effect that may result in normal lipide…

Knowledge, Attitude and Practice of Healthcare Workers Towards Availability of Antiretroviral Pre-Exposure Prohylaxis in Nigeria

Dec 2018 DOI 10.14302/issn.2324-7339.jcrhap-18-2333
Abayomi Joseph AfeCorresponding author

Introduction: The introduction of preexposure prophylaxis (PrEP) against incident HIV infection has changed the epidemiology of disease as continuous treatment with tenofovir and emtricitabine among high risk groups can reduce the relative risk for incident HIV infection by over 90%.However,despite…

Effect of Bone Marrow and Adipose Mesenchymal Stem Cells on Rat Intestinal Injury Induced by Methotrexate

Nov 2018 DOI 10.14302/issn.2640-6403.jtrr-18-2449
Ebtehal Mohammad FCorresponding author

Methotrexate (MTX) is an anti-metabolite in cancer chemotherapy and is associated with various toxicities assigned to inflammation and oxidative stress. The present study was undertaken to corroborate the therapeutic effects of bone marrow mesenchymal stem cells (BM-MSCs) and adipose-derived mesench…

Oligodendrocytes Development and Wnt Signaling Pathway

Oct 2018 DOI 10.14302/issn.2577-2279.ijha-18-2407
Hui FuCorresponding author

Oligodendrocytes are specialized glial cell in central nervous system (CNS) responsible for the formation of myelin sheath around the axon. Oligodendrocyte proliferation and differentiation is regulated by Wnt signaling pathway, at various stages. However, different study groups have described contr…

Changes in Rats’ Liver Structure Induced by Zinc Oxide Nanoparticles and the Possible Protective Role of Vitamin E

Oct 2018 DOI 10.14302/issn.2577-2279.ijha-18-2384
Abdelmonem A. HegazyCorresponding author

Background: Oral ingestion of zinc oxide nanoparticles (ZnONPs) may lead to serious liver injury. Vitamin E (VE) is an important antioxidant factor that can reduce such damage. Aim: This study aimed to evaluate the possible changes that could take place in the liver of adult male albino rats after o…

Acute and Subacute Toxicity Evaluation of the Stem Bark Aqueous Extract of Harungana Madagascariensis in Rodents

Oct 2018 DOI 10.14302/issn.2328-0182.japst-18-2341
Nyemb NyunaїCorresponding author

The present investigation was carried out to evaluate the safety of a stem bark aqueous extract of Harunganamadagascariensis Lam. (Hypericaceae) by determining its potential toxicity after acute and subacute administration in rodents. Acute toxicity tests were carried out in mice and the behavior, d…

Management of Arthrofibrosis of the Knee after an Arthroscopic Meniscectomy with Paralytic Shellfish Poisoning Toxin. Case Report.

Apr 2018 DOI 10.14302/issn.2578-8590.ipj-18-2018
Jaime HinzpeterCorresponding author

Objective: The purpose of this study is to evaluate the use of paralytic shellfish poisoning toxin in a patient with arthrofibrosis of the knee. Arthrofibrosis is a common complication of knee surgery that tends to manifest itself as a limitation of the musculoskeletal ranges. Paralytic shellfish po…

New Pain Management Procedure after Total Knee Arthroplasty: Gonyautoxins are Safe and Effective after A Single Intra-Articular Infiltration

Mar 2018 DOI 10.14302/issn.2578-8590.ipj-18-1952
Nestor LagosCorresponding author

Objective To evaluate the effect of a single intraarticular dose of Gonyautoxins for pain control after Total Knee Arthroplasty (TKA). Subjects 30 consecutive patients with osteoarthritis with Kellgren & Lawrence level of two or more, who required TKA, were enrolled. Methods Subjects receive a singl…

Non-Hodgkin Lymphoma of External Auditory Canal – Uncommon Location and Related Risk Factors

Feb 2018 DOI 10.14302/issn.2641-5518.jcci-17-1880
Bassem A D MettiasCorresponding author

Objective: Presentation of rare case report of primary non-Hodgkin Lymphoma of temporal bone secondary to immunodeficiency after prolonged steroid administration in a diabetic patient. Then review the literature of similar case reports. Method: 49 years old female presented with hearing loss, facial…

Dexamathasone Pulse Therapy in Refractory Childhood Seizure Disorders

Dec 2017 DOI 10.14302/issn.2694-1201.jsn-17-1815
Riaz Ahmed SyedCorresponding author

15 children with variable intractable seizure disorders who were on multiple anti-convulsant medications were treated with pulse monthly doses of parentral dexamethsone varying from 4 – 7 months. EEG and clinical response were assessed periodically as well at the end of the study. 53% of the patient…

Cellular Mechanics and Therapeutic Resistance of the Cancer Relapse

Dec 2017 DOI 10.14302/issn.2766-8630.jrnm-17-1770
Emad Y. MoawadCorresponding author

The aims of this study are to investigate the variation in the mechanical behaviour of the primary cancer from cancer relapse, and measuring the therapeutic resistance acquired by cancer relapse. A431-cultured cells were irradiated for 7 months until 85 Gy. Then, a selected single cell was left to g…

The 5-HT1A Agonist Buspirone Decreases Liver Oxidative Stress and Exerts Protective Effect Against CCl4– Toxicity

Dec 2017 DOI 10.14302/issn.2641-7669.ject-17-1789
M.E.Abdel-Salam OmarCorresponding author Departments of Toxicology and Narcotics

We aimed to study the effect of buspirone, an anxiolytic drug and 5-HT1A agonist on liver injury induced by carbon tetrachloride (CCl4) in rats. Rats were orally treated with CCl4 (2.8 mL/kg in olive oil) along with buspirone at 10, 20 or 30 mg/kg once daily starting with CCl4 and for one week there…

Mild Ovarian Stimulation has Similar Live Birth Rates as Compared with Hyper Stimulation for Treatment of Poor Responding IVF Patients of Advanced Maternal Age

Nov 2017 DOI 10.14302/issn.2576-2818.jfb-17-1812
Wei-Hua WangCorresponding author

The number of patients with poor ovarian response (POR) for in vitro fertilization (IVF) varies from 9 to 25%, especially high in patients of advanced maternal age. Although various stimulation protocols have been developed to improve clinical outcomes in patients with POR, a typical and effective p…

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