Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing
articles matching Investigation — open any to read the full text,
or download the PDF or XML.
Jan 2017 DOI 10.14302/issn.2379-8572.joa-16-1399
Muhammet fatih topuzCorresponding author
Aim: The relation between inflammation and cancer has been known since the 19th century. However, investigations on the pathogenesis and pathophysiology of this relation have begun recently. It was demonstrated that increased neutrophil/lymphocyte ratio is a poor prognostic factor in some malignanci…
Oct 2016 DOI 10.14302/issn.2572-5424.jgm-16-1170
Gul Majid KhanCorresponding author
Background: Skin is one the most important sites for administration of drugs to obtain desired pharmacological effects either locally or through systemic bioavailability; and this has placed the transdermal route of drug delivery as an attractive and as one of the most innovative areas for conductin…
May 2016 DOI 10.14302/issn.2473-1005.jdoi-16-1059
Susanne I. ScottCorresponding author
Allergic angioedema of the airways is a potentially life-threatening condition. The allergen can be difficult to identify. Treatment in the acute phase comprises of antihistamines, steroids, adrenaline and in severe cases prophylactic intubation. Allergic angioedema can be encountered in all medical…
Feb 2016 DOI 10.14302/issn.2328-0182.japst-15-855
Emmanuel Ilesanmi AdeyeyeCorresponding author
An investigation into the proximate, mineral and antinutitional constitutents of natural cocoa powder (NCP), natural cocoa liquor (NCL) and alkalized cocoa powder (ACP) was carried out. Other parameters investigated were: energy values as contributed to the total metabolisable energy by protein, fat…
Jan 2016 DOI 10.14302/issn.2379-8572.joa-15-814
Mohammad FarhadiCorresponding author
Background and Objective: The etiological factors for nasal polyps include infection, inflammation or an imbalance of a metabolic pathway. This study was designed to compare serum Helicobacter pyloriantibodies and H. pylori–DNAs between cases of nasal polyp and controls (nasal fracture). Patients an…
Dec 2015 DOI 10.14302/issn.2576-182X.jbsc-14-582
Mevci OzdemirCorresponding author
Pituitary abscess is extremely rare and often misdiagnosed as pituitary tumor pre-operatively. We document a case of a 64-year-old lady presented to the outpatient department with complaints of headache and blurring vision of right eye for one month. Based on preliminary investigations, a clinical d…
Jun 2015 DOI 10.14302/issn.2470-0436.jos-14-528
Sanjay SrinivasanCorresponding author
Ophthalmology and Visual Sciences, Khoo Teck Puat Hospital, Singapore
A previously healthy 25 year old Chinese male presented with left eye blurring of vision and was diagnosed to have left eye branch retinal vein occlusion. Initial blood investigations and thrombophilia screen were negative. The patient subsequently improved with observation and conservative manageme…
Oct 2014 DOI 10.14302/issn.2471-2140.jaa-14-423
L.S. BilbisCorresponding author
There is increasing evidence of the prevalence manifestations of metabolic syndrome worldwide. Metabolic syndrome is a cluster of abnormalities characterized by hypertension, central obesity, insulin resistance, endothelial dysfunction, dyslipidemia and oxidative stress. All these alterations predis…
Sep 2013 DOI 10.14302/issn.2326-0793.jpgr-13-257
Kathleen O’ConnellCorresponding author
Lapatinib, a small molecule tyrosine kinase inhibitor is currently used in the treatment of HER2-positive breast cancer. The aim of this study was to further understanding of lapatinib response for the development of novel treatment lapatinib-focussed treatment strategies. HER2-overexpressing SKBR3…
Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-12-174
Rajesh RadhakrishnanCorresponding author
Radhakrishnan Rajesh M.Pharm, Asst Professor (Senior Grade), Department of Pharmacy Practice, Manipal College of pharmaceutical Sciences, Manipal University, Manipal- 576 104, Karnataka, India.
Background: In India, Human immunodeficiency (HIV) infected patients with highly active antiretroviral therapy (HAART) are at higher risk of developing adverse drug reactions (ADRs). Objectives: The aim of this study was to characterize the pattern of use of HAART, occurrence, incidence, severity an…