Search results for “Treatment”

A Successful Vancomycin Treatment of Multidrug-Resistant MRSA-Associated Canine Pyoderma

Case Report This report describes a case of diffuse pyoderma in a 10-year-old female dog with hypothyroidism. A previous treatment, without an early diagnosis, including cephalosporin associated with prednisolon resulted to be unsuccessfully. After clinical and microbiological examination in our lab…

Maxillary Constriction with Skeletal Class II Malocclusion - A Comprehensive Treatment Approach.

This case report reiterates the fact that a bilateral posterior crossbite with severe skeletal class II malocclusion in the growth period could be effectively treated by a comprehensive approach with a rapid palatal expansion appliance followed by fixed appliance therapy. A 14-year-old boy presented…

Changes in Gingival Crevicular Fluid Volume and Flow Rate During Orthodontic Treatment

Background: Gingival crevicular fluid (GCF) is regarded as a promising medium for detection of periodontal disease activity. bone loss is a major feature of periodontal disease, although we are unable to determine the time of this bone loss and therefore periodontal disease activity. During orthodon…

Low Laser Therapy Plus Non-Surgical Periodontal Treatment Reduces Interleukin-1 Beta Serum Levels

Objectives: Periodontal disease is associated to widespread systemic inflammation, and further to both cardiovascular morbidity and mortality. Data from intervention studies demonstrated the beneficial effects of periodontal therapy in reducing vascular diseases. The present study was aimed to explo…

Search for New Targets of Deep Brain Stimulation for Epilepsy Treatment

Although clinical trials in refractory epilepsy are currently carried out, the field of deep brain stimulation (DBS) in epilepsy is still at its initial stage. Little is known about where, when and how to stimulate and what would be the short and long consequences. Animal studies might provide clini…

Gene-Eden-VIR: A Potential Natural Treatment for Cervical Cancer

This paper explores the potential of Gene‑Eden‑VIR as an adjunctive approach for cervical cancer prevention or management. The discussion reviews proposed antiviral and immunomodulatory mechanisms, existing evidence, and safety considerations. The authors call for controlled trials to clarify effica…

Anti-Oxidant Phytochemicals as Potential Treatments for Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is responsible for a substantial proportion of severe visual impairment and blindness in people over 50 years of age. Current treatments for AMD are not effective in all patients and a proportion of patients who respond well to the treatment will still eventual…

The Combination of Fractionated Erbium:YAG Laser Skin Microporation and Topical Imiquimod Is A New, Safe And Efficient Strategy for the Treatment of Actinic Keratosis and Basal Cell Carcinoma: Report of Two Pilot Studies

Two pilot studies evaluate fractional Er:YAG laser microporation to enhance topical imiquimod delivery for actinic keratosis and basal cell carcinoma. The approach seeks to increase epidermal penetration while limiting systemic exposure. Early results suggest acceptable tolerability and lesion respo…

Metallic Iron for Water Treatment: Healing A Research Community

Despite two decades of intensive research on using metallic iron (Fe0) for environmental remediation and water treatment, basic concerns about their efficiency still prevail. This communication presents the basic idea of the view that challenges the prevailing paradigm on the operating mode of Fe0/H…

Comment on the Stages of HIV Care Continuum: Considering Treatment for Secondary Prevention among Patients ‘Retained in Care’

This commentary argues for incorporating secondary prevention into the HIV care continuum for patients retained in care. It outlines opportunities to reduce transmission through viral suppression, risk reduction counseling, and supportive services within routine visits.

Determination of the Proteomic Response to Lapatinib Treatment using a Comprehensive and Reproducible Ion-Current-Based Proteomics Strategy

Lapatinib, a small molecule tyrosine kinase inhibitor is currently used in the treatment of HER2-positive breast cancer. The aim of this study was to further understanding of lapatinib response for the development of novel treatment lapatinib-focussed treatment strategies. HER2-overexpressing SKBR3…

Prevalence and Factors Associated with Disclosure of HIV Diagnosis to Infected Children Receiving Antiretroviral Treatment in Public Health Care Facilities in Gauteng, South Africa

HIV infected children who started antiretroviral therapy (ART) in public health facilities in South Africa have survived to older age and disclosure has become an essential part of their care. Available data on HIV disclosure to children were collected much earlier in the provision of ART in South A…

Single Nucleotide Polymorphisms associated with alimentary fatty liver disease are not genetic risk factors for treatment-associated hepatic steatosis in HIV patients on HAART

Analyzing SNPs linked to fatty liver disease, this study finds no association with HAART‑related hepatic steatosis in HIV patients. The work underscores the multifactorial nature of antiretroviral toxicity and points to metabolic and pharmacologic contributors beyond common variants.

RETRACTED: Psychoanalytic Formulations in Psychedelic Assisted Psychotherapy for Treatment Resistant Depression

Rearing Density Impacts Juvenile Bluegill Lepomis macrochirus Growth in a Recirculating Aquaculture System

The effects of rearing density on large juvenile bluegill Lepomis macrochirus growth in recirculating aquaculture systems are relatively unknown. This 63-day study evaluated three initial densities: low (6 kg/m3), intermediate (12 kg/m3), and high (18 kg/m3). Final densities were low (8.1 kg/m3), in…

Advancements in Cancer Gene Therapy: A Comprehensive Review

Gene therapy is a cancer treatment that is superior to chemotherapy, radiotherapy, and other less selective and specifically harmful forms of treatment. It entails the aberrant replacement, alteration, and deletion of a gene within a normal or healthy copy of a gene. Recent trials have made signific…

The Advantages of Employing the Immune Response Mediated by Immunoglobulins in Preclinical and Clinical Research: An Essential Review

Immunoglobulins, commonly known as antibodies, are glycoprotein molecules present on B lymphocytes and within the bloodstream. They are essential components of the immune response, as they detect the harmful molecules of test compounds and stimulate the immune system to manifest proportional counter…

Cyclic Peptides: Prominent Next Generation Targeted Therapies

Cyclic peptides are expected to play a significant role in the future of drug discovery and development. Their unique properties, such as enhanced target affinity, metabolic stability, and favorable pharmokinetic profiles, make them promising candidates for addressing complex therapeutic targets. In…

Incidence and Management of Sural Neuritis Post-Peroneal Tendon Repair – Case Series

Background Sural neuritis is a recognized and common complication resulting from iatrogenic injury, postsurgical or posttraumatic fibrosis, traction injury, or chronic nerve compression. Previously in a case series by Stockton and Brodsky, sural neuritis was reported as a complication in 16.6% of th…

A Unifying Theory of Alzheimer’s and Other Neurodegenerative Diseases

Background/Objectives The etiology and pathophysiology of neurodegenerative diseases are incompletely understood, and the treatments largely ineffective. A unifying theory that explains otherwise poorly understood observations may help to enhance therapeutic outcomes. Methods Here is proposed a unif…