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Oct 2016 DOI 10.14302/issn.2572-3030.jcgb-16-1276
Takuma HayashiCorresponding author
Human uterine leiomyosarcoma (LMS) is neoplastic malignancy that typically arises in tissues of mesenchymal origin. The identification of novel molecular mechanism leading to human uterine LMS formation and the establishment of new therapies has been hampered by several critical points. We earlier r…
Sep 2016 DOI 10.14302/issn.2377-2549.jndc-16-1119
H. SaleemCorresponding author
The FT-IR, FT-Raman and UV-Vis spectra of E-[1-(3'-methylthienyl)-5-Phenyl-2,4-Pentadiene-3-one (MPPO) were recorded. The optimized molecular bond parameters, harmonic frequencies were calculated using B3LYP method with 6-311++G (d,p) basis set.The various normal modes were precisely assigned with t…
Jun 2016 DOI 10.14302/issn.2574-4526.jddd-16-1101
Fernando A. M. HerbellaCorresponding author
Background/Aims: Esophageal motor abnormalities are frequently found in patients with gastroesophageal reflux disease. The effect of bile in esophageal dysmotility is probably secondary to mucosal signaling to the muscular layer and not a transmural process. This study aims to identify the mucosa-mu…
Apr 2016 DOI 10.14302/issn.2377-2549.jndc-16-949
Saleem H.Corresponding author
Department of Physics, Annamalai University, Annamalainagar-608 002, Tamil Nadu, India
Vibrational spectral analysis and first order hyperpolarizability calculations on (E)-N′-(furan-2- ylmethylene) nicotinohydrazide (F2CNH), a novel, organic, hydrozone Schiff base compound was synthesized and its structure was characterized by FT-IR, FT-Raman and UV-visible spectrum. The optimized mo…
Mar 2016 DOI 10.14302/issn.2470-0436.jos-15-739
Vijay P. SarthyCorresponding author
Ciliary neurotrophic factor (CNTF) is a well-tested, neuroprotective agent that has been shown to retard photoreceptor degeneration in several animal models of retinitis pigmentosa. The molecular mechanisms underlying CNTF-mediated neuroprotection are currently not understood. CNTF could act directl…
Jun 2015 DOI 10.14302/issn.2576-182X.jbsc-14-576
Tejpal GuptaCorresponding author
Multi-modality therapy has led to significant improvement in outcomes for childhood medulloblastoma; however, long-term survivors have become more susceptible to late effects of therapy including induction of second malignant neoplasms and even remain at an increased risk of late relapses including…
Jun 2015 DOI 10.14302/issn.2574-4372.jesr-14-607
Michael E. GeuszCorresponding author
Cancer is influenced by the ability of cells to maintain circadian rhythms in molecular and metabolic processes. Disturbance of the underlying circadian timing mechanism in circadian clock cells leads to a higher frequency and more rapid progression of cancer. Cancer stem cells with properties of em…
Jun 2014 DOI 10.14302/issn.2372-6601.jhor-13-379
Takuma HayashiCorresponding author
Sarcomas are neoplastic malignancies that typically arise in tissues of mesenchymal origin. The identification of novel molecular mechanisms leading to sarcoma formation and the establishment of new therapies has been hampered by several critical factors. Human uterine leiomyosarcoma (Ut-LMS) develo…
Feb 2014 DOI 10.14302/ISSN.2372-6601.JHOR-13-344
Emad RaddaouiCorresponding author
Context: Fine needle aspiration cytology (FNA) is increasingly replacing excisional lymph node biopsy in the assessment of various lymphoid lesions. Recent changes in the classification of non-Hodgkin’s lymphoma, namely the WHO (World Health Organization) Classification of Tumors of Haematopoietic a…
Sep 2013 DOI 10.14302/issn.2374-9431.jbd-13-218
Gregory OxenkrugCorresponding author
The increased association between depression and diabetes mellitus is generally acknowledged. Recent studies suggest that depression leads to diabetes.However, the underlying molecular mechanisms for this association remain unclear.Literature and our data indicate that inflammatory and/or stress fac…