Search results for “DNA”

About 55 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching DNA — open any to read the full text, or download the PDF or XML.

Daily Grape Juice Consumption Promotes Weight Loss, Improved Stability and Reduced the DNA Damage in the Elderly

Jul 2020 DOI 10.14302/issn.2379-7835.ijn-20-3448
Caroline DaniCorresponding author

The aim of this study was to determine the influence of chronic supplementation with grape juice (400ml), in modulating the anthropometric and biochemical parameters. Thirty-nine seniors participated and were evaluated at baseline after 30 days. The chronic consumption of grape juice reduced weight,…

A Study on Redox Potential of Phytochemicals and their Impact on DNA

Apr 2020 DOI 10.14302/issn.2575-7881.jdrr-20-3267
Bechan SharmaCorresponding author

The phytochemicals are endowed with antioxidant activities because of the presence of plentiful polyphenols and many other phytochemicals. However, some recent reports have suggested that phytochemicals from certain plant species exhibit DNA damaging properties mainly due to presence of alkaloids. I…

Auricularia Polytricha (Mushroom) Regulates Testicular DNA Expression and Oxidative Stress Markers of Streptozotocin-Induced Diabetic Male Wistar Rat

Mar 2020 DOI 10.14302/issn.2379-7835.ijn-20-3175
Cyril Abang AgborCorresponding author Department of Anatomy, Collage of Basic Medical Sciences, University of Calabar, Nigeria

Local Nigerian men have been using AuriculariaPolytricha as a treatment for sexual dysfunction without supporting evidence from scientific experiments. This study was to investigate the effect of ethanolic extract of A. Polytricha on testicular DNA expression and some oxidative stress markers using…

Genetic Diversity of Large Japanese Field Mouse Apodemus speciosus Populations and Identification of their Food Plant Resources using DNA Barcoding in an Industrial Green Space

May 2018 DOI 10.14302/issn.2637-6075.jpae-18-2062
Taichi FujiiCorresponding author

Estimates of the genetic diversity of Large Japanese field mouse Apodemusspeciosus populations and identification of their plant food resources were conducted in an industrial green space, where were constructed on reclaimed land and belonged to the Aichi Refinery of Idemitsu Kosan Co., Ltd., in Aic…

Dimerization of the BASIC PENTACYSTEINE Domain in Plant GAGA-Factors is Mediated by Disulfide Bonds and Required for DNA-Binding.

Aug 2017 DOI 10.14302/issn.2638-4469.japb-17-1563
Dierk WankeCorresponding author

GAGA-binding proteins in plants are encoded by the BARLEY B-RECOMBINANT / BASIC PENTACYSTEINE (BBR/BPC) family, which can be spilt into several groups on the basis of sequence divergence. The proteins of the different groups share an evolutionary conserved BASIC PENTACYSTEINE (BPC) domain at their v…

Journal of Neoplasms Open Access

Tumor Growth Dynamics: Dietary Fish Oil Induced Inhibition of Human Breast Carcinoma Growth, A Phenomenon of Reduced Cellular DNA Synthesis or Increased Cell Loss?

Jul 2017 DOI 10.14302/issn.2639-1716.jn-17-1495
Michael J GonzalezCorresponding author

Diets high in unsaturated fatty acids, especially those containing high levels of linoleic acid, e.g., corn oil, enhance mammary gland tumorigenesis in experimental animals. In contrast, diets high in long-chain polyunsaturated fatty acids such as eicosapentaenoic (EPA) and docosahexaenoic (DHA), e.…

High-Throughput Complex Disease Modeling for Ethical Drug Discovery: Clinical Relevance of a NAM Platform for Cancer Biomarker Development

May 2026 DOI 10.14302/issn.2572-3030.jcgb-26-6307
Arne-C. FaisstCorresponding author

The development of tumor biomarkers derived from blood, or its components, has become pivotal in advancing early cancer diagnosis. Malignant transformations induce cancer-specific alterations in the transcriptome, proteome, and secretome of tumor cells. Recent studies highlighted similar alterations…

Proteomic and Genomic Techniques in Medical Research: Applications in Cancer, Diagnostics, and Personalized Medicine

Nov 2025 DOI 10.14302/issn.2326-0793.jpgr-25-5573
Oghenetega E. ImiruayeCorresponding author

Advancements in proteomic and genomic technologies have transformed molecular biology by enabling comprehensive analysis of biological systems at the molecular level. This literature review explores the evolution, methodologies, and practical applications of key proteomic and genomic techniques. In…

Genotypic Diversity among Salmonella Typhi Isolated from Children Living in Informal Settlements in Nairobi, Kenya

Sep 2024 DOI 10.14302/issn.2690-4721.ijcm-24-5195
Susan Mutile KavaiCorresponding author

The persistence of multidrug-resistant (MDR) Salmonella Typhi (S. Typhi) is a challenge especially in regions where typhoid is endemic. Surveillance of circulating genotypes of MDR S. Typhi is crucial in typhoid acute cases and carriers. This study aimed to investigate genotypic diversity of S. Typh…

The Chromosomes of Dictyostelium Giganteum

Jul 2024 DOI 10.14302/oap.jc-23-4781
Jayarama S. KadandaleCorresponding author

As a first step towards clarifying the basis of the cooperation and conflict seen in chimeric binary mixes of Dictyostelium giganteum, we examined the karyotype of six natural isolates. All six had 5 haploid chromosomes. No meiotic figures were seen. Fluorescence in-situ hybridization was carried ou…

Cervico-Vaginal Smear Abnormalities in a Patient with Pemphigus Vulgaris

Mar 2024 DOI 10.14302/issn.2997-2108.jcc-20-3675
Zheng YuanCorresponding author

Pemphigus vulgaris is an autoimmune-mediated blistering disease. Cervical involvement is rare. A 38 year old nulliparous woman with PV on oral prednisolone and azathioprine was referred to the Gynaecology service for an abnormal cervical cytological smear showing low-grade squamous intraepithelial l…

RET 898-901Del mutant, a variant of unknown significance, has a durable response to Pralsetinib in a Medullary Thyroid Carcinoma patient

Sep 2023 DOI 10.14302/issn.2574-4496.jtc-23-4722
Patrick J. ConwayCorresponding author

Background Patients with distant metastatic Medullary Thyroid Carcinoma (MTC) have an estimated 40% ten-year survival rate. Gain of function mutations in the REarranged during Transfection or RET gene in MTC can result in an aggressive phenotype resistant to traditional therapy. In this case report,…

Detection of Smuggled Genetically Modified Crops and Assessment of its Environmental Impact in the Ethio -Sudan Trans Boundary Area, North West Ethiopia

Apr 2023 DOI 10.14302/issn.2576-6694.jbbs-22-4390
Nega BerhaneCorresponding author

Background The genetic material of the genetically modified crop has been altered to develop the necessary insect resistance features by introducing genes from the Bt (Bacillus thuringiensis) bacterium. The objective of this study was to find smuggled GM Bt crops in the Metema farming area and exami…

Correlating 13C Isotope in Oligomeric Proanthocyanidins with their Anticancer Properties

Oct 2022 DOI 10.14302/issn.2572-3030.jcgb-22-4284
Reginald B. LittleCorresponding author

Upon considering the anticancer effects of larger oligomeric proanthocyanidins and observing various papers reporting the high resolution mass spectroscopy of the oligomeric proanthocyanidins, it is determined that the unusual 13C enrichment in some plant oligomeric proanthocyanidins may be responsi…

Molecular Detection of Mycoplasma Gallisepticum and Mycoplasma Synoviae Infection in Poultry

Aug 2022 DOI 10.14302/issn.2835-2165.jfsh-22-4263
Waqar MazharCorresponding author

In Pakistan, production of poultry has been evolved as a good alternate of beef and mutton. In this study multiplex PCR approaches were adopted to differentiate and detect avian mycoplasma in a single PCR reaction as a step forward in the economization of PCR detection. From the total of 25 samples,…

Targeting Mutational Landscape of TP53 in patients diagnosed with Oral Cancer living in Senegal

Mar 2022 DOI 10.14302/issn.2572-3030.jcgb-22-4121
Pierre Diaga SARRCorresponding author Laboratory of Clinical Cytology, Cytogenetics and Reproduction Biology, Aristide Le Dantec Hospital, Dakar-Senegal

Introduction Genomic mutations in TP53 gene in association with etiological risk factors have been associated with oral carcinogenesis. Herein, we screened for genomic variants of TP53 predisposing to oral cancers in Senegalese patients. Methodology 88 patients with confirmed diagnostic were recruit…

Challenger and Propose Novel Methods and Techniques for Prevention, Prognosis, Diagnosis, Imaging, Screening, Treatment and Management of Lung Cancer

Feb 2022
Ricardo GobatoCorresponding author

Using samples of small cell lung tumors, a research team led by biologist Dr. Raymond discovered two new ways to induce tumor cell death. By activating ferroptosis, one of two subtypes of tumor cells can be targeted: first, iron-dependent cell death due to oxidative stress, and second, oxidative str…

Six Fractal Codes of Biological Life Unifying ATOMS, WAVES and INFORMATION: Perspectives in Exobiology, Cancers Basic Research and Artificial Intelligence Biomimetism Decisions Making

Oct 2021 DOI 10.14302/issn.2641-5526.jmid-21-3900
Jean-claude PerezCorresponding author

In this theoretical discovery of a law of Life, there is MATHEMATICS (Geometry, Bits and Numbers) that UNIFY 3 universes as complementary as ATOMIC MASS, WAVES, and INFORMATION (DNA, RNA and Amino Acids). The discovery of a simple numerical formula for the projection of all the atomic mass of life-s…

Some Regulation Mechanisms of Candidate Genes for Human Cardiovascular Diseases

Mar 2021 DOI 10.14302/issn.2329-9487.jhc-21-3742
Tesfaye SisayCorresponding author

Cardiovascular disease is actually a major cause of mortality, illness and hospitalization worldwide. Several risk factors have been identified that are strongly associated with the development of cardiovascular disease. Public prevention strategies have relied predominately on managing environmenta…

COVID-19 Vaccine Development: Insights, Prospects and Challenges

Aug 2020 DOI 10.14302/issn.2691-8862.jvat-20-3513
Jainish PatelCorresponding author

This paper explores the trends, issues and challenges confronting the successful vaccine development for the novel Coronavirus disease (COVID-19). Right from the commencement of the COVID-19 pandemic, no drugs or vaccine has been developed nor approved for treating those down with COVID-19. This yea…

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