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Sep 2026
Yilkal Tariku BelayCorresponding author
Immunoglobulins, commonly known as antibodies, are glycoprotein molecules present on B lymphocytes and within the bloodstream. They are essential components of the immune response, as they detect the harmful molecules of test compounds and stimulate the immune system to manifest proportional counter…
Feb 2024 DOI 10.14302/issn.2379-7835.ijn-24-4938
Mina SuhCorresponding author
Public health interest in vaccinations and immune protection has increased with the COVID-19 pandemic. Dairy products are an important source of protein and other nutrients, and there are unresolved research questions regarding the potential health impact of dairy products on the enhancement of immu…
Jan 2024 DOI 10.14302/issn.2328-0182.japst-23-4771
Yilkal Tariku BelayCorresponding author
Background Immunoglobulins are bio-receptors found embedded in the cell membrane with a biological role that detects the harmful molecules of a test compound. These bio-receptors interface between a biological system and its external environment that transduce information to the effector via interme…
Mar 2023 DOI 10.14302/issn.2474-7785.jarh-22-4381
Yilkal Tariku BelayCorresponding author
Background Ageing is a life process in which progressive molecular, cellular, physiological and anatomical changes manifesting in humans and animals including other organisms lead to the decline of biological functions. Immunoglobulins (Igs) are glycoprotein molecules produced by white blood cells m…
Aug 2017 DOI 10.14302/issn.2575-1212.jvhc-17-1662
Fernando Díaz OteroCorresponding author
Immunization of cattle with the bacillus Calmette-Guérin (BCG) vaccine, especially neonates, induces protection against Mycobacterium bovis (M. bovis) and has been proposed as a strategy for bovine tuberculosis (bTB) control. Therefore, the aim of this study was to evaluate the immune response induc…
Jun 2017 DOI 10.14302/issn.2690-4721.ijcm-17-1533
Soon Hoe Ho BSc (Hon)Corresponding author
This essay draws on recent evidences from SIV vaccination studies in rhesus macaques to argue for the potential importance of HIV-1-specific CD8+ T cells restricted by the non-classical major histocompatibility complex, HLA-E, in controlling HIV-1 replication. It then seeks to present a possible met…
Jul 2023 DOI 10.14302/issn.2643-2811.jmbr-23-4556
Raul IseaCorresponding author
The present work shows that it is possible to analytically solve a general model to explain the transmission dynamics of SARS-CoV-2. First, the within-host model is described, and later a between-host model, where the coupling between them is the viral load of SARS-CoV-2. The within-host model descr…
Jun 2022 DOI 10.14302/issn.2328-0182.japst-22-4193
Yilkal Tariku BelayCorresponding author
The strategy for safe drug discovery and development has limited clinical success as compared to wasted time and resources annually. This is due to the fact that the results of multiphase preclinical trials are less likely to make an accurate early prediction on the safety of test compounds to progr…
Jan 2022 DOI 10.14302/issn.2692-1537.ijcv-21-4051
Mayyadah AlabdelyCorresponding author
Background As COVID-19 immunomodulation has been a part of interest for studies, it has been found that severe coronavirus disease 2019 (COVID-19) is associated with hyper-inflammatory response and increased levels of interleukin-6 (IL-6) and interleukin-10 (IL-10). This can progress to cytokine sto…
Dec 2021 DOI 10.14302/issn.2575-1212.jvhc-21-4034
Fernando Díaz-Otero,Corresponding author
CENID-Salud Animal e Inocuidad. Instituto Nacional de Investigaciones Forestales, Agrícolas y Pecuarias (INIFAP). Carretera México-Toluca, Km. 15.5, C.P. 05110, Ciudad de México, México.
In bovine tuberculosis (bTB), cellular, humoral, or both types of immune responses have been observed. The purpose of this study was to examine the immune status of tuberculous cows based on the differential cytokine gene expression associated with Th1 (IFN-γ, IL-2), or Th2 (IL-4, IL-10) responses.…
Nov 2021 DOI 10.14302/issn.2690-4837.ijip-21-4015
Caitlin A. Connor DAOM PGDip AMP EHP-CCorresponding author
Copper (Cu) has a strong impact on the function of the immune system through several different pathways. These impacts include helping the function of monocytes, neutrophils, and macrophages, and enhancing Natural Killer cells’ activities. Cu also has a role in antimicrobial properties and inflammat…
Jul 2021 DOI 10.14302/issn.2474-7785.jarh-21-3850
Snehasis JanaCorresponding author
The aim of the study was to evaluate the immunomodulatory activity of the Biofield Treated/Blessed proprietary test formulation consisting of essential ingredients viz. minerals (zinc, magnesium, iron, and copper) and vitamins (B6, B12, and D3) in male Sprague Dawley rats. Each ingredient of the tes…
Jan 2021 DOI 10.14302/issn.2692-1537.ijcv-20-3685
Hoda ElkhenanyCorresponding author
The current uncontrollable outbreak of novel coronavirus (COVID-19) has unleashed severe global consequences in all aspects of life and society, bringing the whole world to a complete halt and has modeled significant threats to the global economy. The COVID-19 infection manifests with flu-like sympt…
Dec 2020 DOI 10.14302/issn.2474-7785.jarh-20-3662
Ray MarksCorresponding author
Background Most current Corona virus or COVID-19 pandemic deaths have been found to occur among populations older than 65 years of age, who often suffer from the presence of an array of chronic diseases that may be related to a co-occurring vitamin D deficiency. Another factor affecting older adults…
Sep 2020 DOI 10.14302/issn.2379-7835.ijn-20-3369
Bal Kishan GuptaCorresponding author
Background Since swine flu has been declared pandemic in 2009 it has become a major challenging public-health problem associated with high morbidity and mortality. 25(OH)D deficiency is also pandemic and has been reported to be clinically correlated with decreased immunity and respiratory infections…
Sep 2020 DOI 10.14302/issn.2694-2283.jsem-20-3539
Awoke TibebuCorresponding author
The following document provides important information that everybody know about physical exercise as a means of managing COVID-19. It addresses the health benefits of physical exercise on our body’s immune system, and stress reduction. Already today in the entire world, coronavirus is now the leadin…
Aug 2020 DOI 10.14302/issn.2692-1537.ijcv-20-3492
Kevin K. LauCorresponding author
Mannose binding lectins (MBL), a key molecule in our innate immune response, contributes to host defense against coronaviruses such as SARS-CoV. This article reviews the role of MBL in the innate immune response against coronavirus infections, highlights evidence of MBL’s significance, and suggests…
May 2020 DOI 10.14302/issn.2641-7669.ject-20-3313
A.J ThatheyusCorresponding author
PG & Research Department of Zoology, The American College, Madurai, Tamil Nadu, India.
Industrial effluents containing heavy metals may reach aquatic systems either through direct discharge or surface runoff and cause damage to aquatic organisms affecting their immune system and health. Hence the present study has been undertaken to observe the effects of hexavalent chromium on the WB…
Mar 2019 DOI 10.14302/issn.2641-5518.jcci-19-2626
Giampietro BertasiCorresponding author
Matrices or tissue scaffolds provide a collagen structure for tissue remodelling while the removal of viable cells aims to minimize or prevent inflammatory or immunogenic response. Allograft collagen scaffold can support the patient’s own cellular ingrowth, ingeneered to minimize an immune response…
Mar 2019 DOI 10.14302/issn.2379-7835.ijn-19-2578
Farid E. AhmedCorresponding author
We present below a mechanistic cellular and molecular approaches for the development of Anti-Inflammatory biomarkersof Probiotic Bacteria in Fermented Foods. Probiotics are live microorganisms that promote human health by counteracting the noxious toxic gut microflora in human intestine, by modulati…