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We investigated physical steric and thermal stability effects induced by cholesterol and polyethylene glycol (PEG) in liposomes encapsulated with riboflavin. The composition of liposome was varied systematically to decipher the individual and combined effects of cholesterol and PEG on the stabilizat…
This review discusses lipid assemblies—from liposomes to solid lipid nanoparticles—as platforms for drug delivery. It covers design principles, targeting strategies, and manufacturing considerations.
PEGylation is a well-established strategy for improving the target specificity, circulation time and stability of liposomes, thereby improving their stealth properties. This brief review provides an insight on the composition of PEGylated liposomes and the characteristics that dictate the functional…