Search results for “Mass spectrometry”

About 14 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Mass spectrometry — open any to read the full text, or download the PDF or XML.

Liquid Chromatography-Mass Spectrometry (LC-MS) Applications in Food Safety–Review

Dec 2024 DOI 10.14302/issn.2835-2165.jfsh-24-5371
Pradeep SarkateCorresponding author

One of the primary goals and aims of studying chemistry in society is the promotion of the well-being of humanity and the sustainable utilization of the available resources. Chemistry has played a significant role in water treatment, food production, energy production, and medicine, among other crit…

Research Gaps in Contaminants of Emerging Concern (CECs): Routes to the Standardization of Chemical Test Methods By GC/LC-Mass Spectrometry: A Review

Jun 2023 DOI 10.14302/issn.2377-2549.jndc-23-4615
Thavrin ManickumCorresponding author

A literature review was undertaken with a focus on 1) identifying the research gaps regarding CECs, 2) identifying the most common ones, and 3) identifying the typical analytical methods/technologies employed, for their analysis. A total of 214 papers were noted, with a total of 21 review articles (…

Distinguish Thyroid Malignant from Benign Alterations using Trace Element Contents in Nodular Tissue determined by Neutron Activation and Inductively Coupled Plasma Mass Spectrometry

Apr 2022 DOI 10.14302/issn.2689-5773.jcdp-22-4123
Vladimir ZaichickCorresponding author

Background Thyroid benign (TBN) and malignant (TMN) nodules are a common thyroid lesion. The differentiation of TMN often remains a clinical challenge and further improvements of TMN diagnostic accuracy are warranted. The aim of present study was to evaluate possibilities of using differences in tra…

Ovarian Cancer Identification Based on Feature Weighting for High-Throughput Mass Spectrometry Data

Mar 2018
Xiaoping LiuCorresponding author

An important use of proteomics data from Mass Spectrometry (MS) is the classification of tumor types with respect to peptides in specific cancer types. It is highly critical to find an optimal set of markers among specific cancer peptides whose expression can be clinically utilized to build assays f…

Discovery and Quantification in Mass Spectrometry-Based Proteomics

Jan 2014 DOI 10.14302/issn.2326-0793.jpgr-13-357
Emily I. ChenCorresponding author

Mass spectrometry (MS) has been successfully used to analyze biological samples and advances of MS-based approaches have turn MS data from largely qualitative to quantitative. These MS-based quantitative approaches using label-free, tags, or stable isotope labeling have their own strengths and limit…

Rapid and Sensitive High-Performance Liquid Chromatography/Tandem Mass Spectrometry Method for Determination of Danshensu in Rat Plasma

Nov 2013 DOI 10.14302/issn.2326-0793.jpgr-13-291
Yue-sheng WangCorresponding author

A sensitive, specific and rapid high-performance liquid chromatography/tandem mass spectrometry (hplc–ms/ms) method has been developed and validated for the determination of danshensu (dss) in rat plasma in the present study. The analytes were separated on a c18 column (50 mm×2.1 mm, 1.7 μm) and a t…

Liquid Chromatography Tandem Mass Spectrometry Method for Determination of Febuxostat in Human Plasma to Support A Bioequivalence Study

Mar 2013 DOI 10.14302/issn.2328-0182.japst-12-173
Bhavin N. PatelCorresponding author

A reliable, selective and sensitive liquid chromatography-tandem mass spectrometry (LC-ESI-MS/MS) assay has been proposed for the determination of febuxostat in human plasma using indomethacin as the internal standard (IS). The analyte and IS were extracted from 200 µL of human plasma via liquid-liq…

Optimization and ZSPORE Analysis of Affinity Purification Coupled with Tandem Mass Spectrometry in Mammalian Cells

Dec 2012 DOI 10.14302/issn.2326-0793.jpgr-12-100
Shitao LiCorresponding author

Defining protein-protein interactions is essential for understanding the mechanisms by which cells regulate basic functions, such as metabolism, transcription, and signal transduction. Affinity purification followed by tandem mass spectrometry (AP-MS) has application for discovery of new interactors…

Proteomic and Genomic Techniques in Medical Research: Applications in Cancer, Diagnostics, and Personalized Medicine

Nov 2025 DOI 10.14302/issn.2326-0793.jpgr-25-5573
Oghenetega E. ImiruayeCorresponding author

Advancements in proteomic and genomic technologies have transformed molecular biology by enabling comprehensive analysis of biological systems at the molecular level. This literature review explores the evolution, methodologies, and practical applications of key proteomic and genomic techniques. In…

Study of the Consciousness Energy Healing Treatment and It’s Effect on the Isotopic Abundance Ratio of Ascorbic Acid (Vitamin C)

Apr 2021 DOI 10.14302/issn.2689-2855.jan-21-3771
Snehasis JanaCorresponding author

Ascorbic acid is a water-soluble vitamin (Vitamin C) essential for both the plants and animals for the metabolic process. In this study, the liquid chromatography-mass spectrometry (LC-MS) analytical technique was used to characterize the structural properties and isotopic abundance ratio to evaluat…

Molecular Analysis of 6-pyruvoyltetrahydropterin Synthase Gene in Atypical Phenylketonuric Egyptian Patients

Jul 2020 DOI 10.14302/issn.2576-6694.jbbs-20-3450
Magdy M. MahmoudCorresponding author

Background Hyperphenylalaninemia (HPA) combined with neurological signs due to impaired catecholamine, dopamine and serotonin synthesis. Symptoms may appears in first week of life but most seen in age of 4 months. Atypical PKU disease caused mainly by deficiency in 6-pyruvoyltetrahydropterin synthas…

Study of Organic Pollutants in the Muscles of fish Collected from El-Mahmodia Stream at El-Beheira Governorate, Egypt

Oct 2019 DOI 10.14302/issn.2691-6622.ijar-19-2991
E H RadwanCorresponding author

The purpose of this study is to evaluate the impact of organic pollution of EL-Mahmodia canal on the fish (Oreochromis niloticus)muscles tissues collected from two sites at EL-Mahmodia canal in summer and winter 2017. EL-Mahmodia canal is exposed to excessive of effluents which impact fish. The pres…

Identification and Quantification of an Adulterant in a Dietary Supplement Marketed for Sexual Enhancement

Oct 2018 DOI 10.14302/issn.2328-0182.japst-18-2344
Liliana MuschiettiCorresponding author

In recent years, the consumption of dietary supplements (DS) has increased worldwide. In Argentina, approximately 14 million DS units were sold between 2015 and 2017. The adulteration of DS with active pharmaceutical ingredients or their analogues has been reported. This represents an alarming emerg…

Quantitative Proteomics Using 15N SILAC Mouse

Jul 2013 DOI 10.14302/issn.2326-0793.jpgr-13-252
Emily I. ChenCorresponding author

In biomedical research the use of mammalian tissues is crucial to increase our understanding of complex human diseases. Mass spectrometry-based proteomic approach has become the most powerful tool of studying large-scale protein expression profiles in mammalian tissues. To perform global proteome an…

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