International Journal of Negative Results
Open Access
Pnpla3/Adiponutrin Deficiency in Mice Does Not Contribute to Steatohepatitis, Fibrosis or Cholestatic Liver Injury
Mar 2026 DOI 10.14302/issn.2641-9181.ijnr-25-5844
Michael TraunerCorresponding author
A sequence variation (I148M) in the patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene has been linked to metabolic dysfunction-associated steatotic liver disease (MASLD) and the progression of MASLD and other chronic liver diseases towards fibrosis and cancer. To elucidate the rol…