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Apr 2018 DOI 10.14302/issn.2326-0793.jpgr-18-2004
Pervez AnwarCorresponding author
Human proteome project was revolutionized about 40 years ago with purpose of summarizing whole proteomic data at one place. It was launched after human genome project to map and observe all proteins. The goal related proteomic study is to draft the entire human proteome in disease diagnosis by using…
Jan 2014 DOI 10.14302/issn.2326-0793.jpgr-sp1-edt-1
Leonid TarassishinCorresponding author
A primer explains how proteomics scales from single‑protein analysis to whole‑organism studies, touching on technologies, bioinformatics, and applications.
Jul 2013 DOI 10.14302/issn.2326-0793.jpgr-13-207
Joanna FlorosCorresponding author
Surfactant protein A (SP-A) plays a number of roles in lung host defense and innate immunity. There are two human genes, SFTPA1 and SFTPA2, and evidence indicates that the function of SP-A1 and SP-A2 proteins differ in several respects. To investigate the impact of SP-A1 and SP-A2 on the alveolar ma…
May 2026 DOI 10.14302/issn.2572-3030.jcgb-26-6307
Arne-C. FaisstCorresponding author
The development of tumor biomarkers derived from blood, or its components, has become pivotal in advancing early cancer diagnosis. Malignant transformations induce cancer-specific alterations in the transcriptome, proteome, and secretome of tumor cells. Recent studies highlighted similar alterations…
Jul 2017 DOI 10.14302/issn.2326-0793.JPGR-17-1571
Henrique C. P. FigueiredoCorresponding author
Perkinsus marinus is an intracellular parasitic protozoan that is responsible for serious disease epizootics in marine bivalve mollusks worldwide. Despite all available information on P. marinus genomics, more baseline data is required at the proteomic level. Our aim was to study the proteome profil…
Jan 2014 DOI 10.14302/issn.2326-0793.jpgr-13-357
Emily I. ChenCorresponding author
Mass spectrometry (MS) has been successfully used to analyze biological samples and advances of MS-based approaches have turn MS data from largely qualitative to quantitative. These MS-based quantitative approaches using label-free, tags, or stable isotope labeling have their own strengths and limit…
Sep 2013 DOI 10.14302/issn.2326-0793.jpgr-13-257
Kathleen O’ConnellCorresponding author
Lapatinib, a small molecule tyrosine kinase inhibitor is currently used in the treatment of HER2-positive breast cancer. The aim of this study was to further understanding of lapatinib response for the development of novel treatment lapatinib-focussed treatment strategies. HER2-overexpressing SKBR3…
Jul 2013 DOI 10.14302/issn.2326-0793.jpgr-13-252
Emily I. ChenCorresponding author
In biomedical research the use of mammalian tissues is crucial to increase our understanding of complex human diseases. Mass spectrometry-based proteomic approach has become the most powerful tool of studying large-scale protein expression profiles in mammalian tissues. To perform global proteome an…