Search results for “Therapeutics”

About 13 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Therapeutics — open any to read the full text, or download the PDF or XML.

Review: The Role of Human Papillomavirus in Virus-Induced Carcinogenesis

Dec 2025 DOI 10.14302/issn.2997-2108.jcc-25-5657
Zahraa M EssamCorresponding author

Viral infections contribute to a significant proportion of human cancers, with human papillomavirus (HPV) being one of the most well-established oncogenic viruses. This review summarizes HPV biology, transmission, classification, molecular mechanisms of carcinogenesis, epidemiology of HPV-associated…

Persistent Neovascular Exudation in Patients with Exudative Age-Related Macular Degeneration who have Choroid Imaging Biomarkers of Non-Neovascular Choroidal Pathology: Simultaneous Choroidal Hyperpermeability and Angiogenesis

Nov 2025 DOI 10.14302/issn.2470-0436.jos-25-5503
Mark H. NelsonCorresponding author

Purpose Create a new diagnostic and therapeutic framework for patients with Exudative Age-Related Macular Degeneration (ARMD) and choroid imaging biomarkers of non-neovascular choroidal pathology who have persistent neovascular exudation during the course of monotherapeutic interventions. Methods Re…

Generation of a Single-Domain Antibody against Isolated Escherichia Coli that Causes Camel-Calf Death

Mar 2021 DOI 10.14302/issn.2575-1212.jvhc-21-3767
Faysal Abdishakur HassanCorresponding author

Antibodies and antibody fragments, especially single-domain antibodies known as nanobodies, are important tools in diagnostics, research, and therapeutics. In a conventional antibody, light and heavy chains contribute to the formation of the antigen binding site. In addition to conventional antibodi…

Effects of Selected Secondary Metabolites in Leaf Extract of Jatropha Tanjorensis on Some Gonadal Hormones in Male Wistar Rats

Jul 2020 DOI 10.14302/issn.2576-6694.jbbs-20-3466
John AkighirCorresponding author Department of Biochemistry, College of Science, Federal University of Agriculture, Makurdi P.M.B. 2373 (970001) Nigeria

Background and Objective The use of medicinal plants in industrialized societies for extraction and development of many drugs and other chemotherapeutics and traditionally for herbal remedies has increased in recent times. Plant–based medicine is essential in health care services with about 80% glob…

Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges in Toxicology Practice

Apr 2020 DOI 10.14302/issn.2691-8862.jvat-20-3314
Shimaa M. MotaweiCorresponding author

This article reviews toxicology practice challenges during COVID‑19, including laboratory safety, chemical exposures, therapeutics, and public health messaging. It identifies research needs and operational adaptations to support preparedness for future events.

pH-Sensitive Nanomedicine for Treating Gynaecological Cancers

Feb 2020 DOI 10.14302/issn.2381-862X.jwrh-19-3143
Pramod Vishwanath PrasadCorresponding author

Emergence of various nanoscale drug carrier platforms as Drug Delivery Systems (DDS) has revolutionized the field of medicine.Nonetheless, theside-effects due to non-specific distribution of anticancer therapeutics in normal, healthy tissues remain to be a prime pitfall in curing cancers. Therefore,…

Avant Garde Alleviation -Cancer Immunotherapy

Nov 2019 DOI 10.14302/issn.2689-5773.jcdp-19-3061
Anubha BajajCorresponding author

Novel cancer therapeutics are superior and  prevalent in the current scenario although a subset may not be satisfactorily alleviated or undergo disease relapse with the adoption of conventional chemotherapeutic agents.  Cancer cells can comfortably elude immune destruction as  interaction of cancer…

Type-2 Diabetes and Gene Therapy: The Promise of CRISPR Gene Therapy in type-2 Diabetes Mellitus

Sep 2019 DOI 10.14302/issn.2574-450X.jom-19-3001
Sikandar Hayat KhanCorresponding author

Gene therapy has entered a new era with the dawn of CRISPR/Cas9 technology which though were always available in nature but rediscovered to tame into a real-tlife genome editing tool. With the modernization upsurge and changes in ways the “homo sapiens” survived on this planet from hunger to current…

Physiology of Distinct Modes of Muscular Contraction

Oct 2018 DOI 10.14302/issn.2578-8590.ipj-18-2441
Nasim HabibzadehCorresponding author

Physiological changes in musculature allow widespread movements in human body. Correspondingly, varying in muscle prototypes characterise direct different training paradigms in therapeutics practice or can governs athletic performances. Mode of muscle contraction type are isometric, concentric or ec…

MicroRNA: New Era for Therapeutic Strategy in Ischaemic Heart Disease

Jun 2017 DOI 10.14302/issn.2329-9487.jhc-17-1536
Md. Kamrul HossainCorresponding author

Over the last few decades, many research works highlighted the role of miRNAs on cardiac diseases. Ischaemic heart disease (IHD) or coronary heart disease is a condition that is mainly caused by atherosclerosis. It has been established that microribonucleic acids regulate many factors that are invol…

Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression

May 2015 DOI 10.14302/issn.2471-7061.jcrc-14-574
Rosalyn B. IrbyCorresponding author

Colon cancer has a five-year survival of 64.7%, and about 50,000 people are expected to die from colon cancer this year. Patients with metastatic colorectal cancer have a significantly worse prognosis, a 12.9% five-year survival. This emphasizes the need for strategies to inhibit the growth and meta…

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