Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing
articles matching age. — open any to read the full text,
or download the PDF or XML.
Aug 2026
Manjula Reddy PallerlaCorresponding author
Cyclic peptides are expected to play a significant role in the future of drug discovery and development. Their unique properties, such as enhanced target affinity, metabolic stability, and favorable pharmokinetic profiles, make them promising candidates for addressing complex therapeutic targets. In…
Jul 2026 DOI 10.14302/issn.2471-7061.jcrc-26-6320
Chun R. ChaoCorresponding author
Background The incidence of early-onset colorectal cancer (eoCRC), diagnosed at age <50 years, is increasing in the United States. Prior studies using national and state cancer databases have observed higher eoCRC mortality after diagnosis among non-Hispanic Black (NHB) patients. These studies, howe…
Jun 2026 DOI 10.14302/issn.2574-4496.jtc-26-6304
Omayma ElshafieCorresponding author
Objective To evaluate the treatment outcomes of patients with Differentiated thyroid cancer (DTC) who underwent total thyroidectomy followed by RAI therapy at the Sultan Qaboos Comprehensive Cancer Care and Research Centre (SQCCCRC) in Oman. Methods This is a retrospective observational clinical stu…
May 2026 DOI 10.14302/issn.3070-3379.jwc-26-6201
Bruce R. HodgsonCorresponding author
A sustainable global net-zero carbon emission is when emissions are equivalent to the uptake of carbon by global terrestrial and aquatic plants. To meet that objective, an approximate 50% reduction of fossil-fuel emissions was estimated for net-zero by 2050 using carbon dioxide concentrations and ma…
Mar 2026 DOI 10.14302/issn.2372-6601.jhor-25-5938
Caine ReganCorresponding author
Acquired haemophilia (AHA) is a rare coagulation disorder secondary to autoantibodies against coagulation factor, most commonly factor VIII with potential for life threatening bleeding episodes. We report a case of an 88-year-old female presenting with frank haematuria three weeks after catheter ins…
Jan 2026
Kirandeep KaurCorresponding author
Background Female infertility has always been an issue and social stigma in India and it’s not only the matter of physical health of the female but also related to psychological health and the social status of the women. The diagnosis of this problem criterion requires medical symptoms for the condi…
Dec 2025 DOI 10.14302/issn.2691-5014.jphn-25-5577
Mark GormleyCorresponding author
Infants with single ventricle (SV) physiology are at increased risk of undernutrition, which can contribute to adverse outcomes. This is a retrospective case series examining factors associated with undernutrition in patients with SV physiology at one year of age. It includes 56 infants from a singl…
Dec 2025
Arnold WaineCorresponding author
Background Intravenous Fluids use during surgery is a common practice for many reasons. However recent evaluation of perioperative abdominal surgery patients have poised many issues. Mostly on the type of fluid and quantity of volume usage on major abdominal surgery. Many studies into this aspect of…
Oct 2025 DOI 10.14302/issn.3070-2313.jeh-25-5757
David P. AustinCorresponding author
The Ames dwarf mice have a recessive mutation of the PROP-1 gene that produces hereditary dwarfism. The abnormality is responsible for an anterior-pituitary deficiency that results in a substantial reduction of growth hormone, thyroid-stimulating hormone, and prolactin. These mice are smaller in siz…
Oct 2025 DOI 10.14302/issn.2693-1176.ijgh-25-5729
Gbadebo Collins AdeyanjuCorresponding author
Background In sub-Saharan Africa, where many countries continue to experience high burdens of vaccine-preventable diseases, increasing immunization access have been a priority for the governments and international organizations such as Gavi, the Vaccine Alliance. Over 40 Gavi-supported African count…
Aug 2025 DOI 10.14302/issn.2379-8572.joa-25-5645
Berdia BeridzeCorresponding author
Purpose The objective of this prospective case-control study was to perform translation, cross-cultural adaptation, and validation of the sino-nasal outcome test 22 (SNOT-22) into the Georgian language. Methods The translation and validation of the SNOT -22 questionnaire was performed using the forw…
Aug 2025 DOI 10.14302/issn.3070-1937.ijbt-25-5408
Mohammad Taher HojjatiCorresponding author
Background and Objectives Platelets are small, anucleate blood cells produced in the bone marrow, primarily involved in blood coagulation. Platelet concentrate is a vital blood product with extensive applications. However, its short lifespan and limited donor availability pose global challenges. Thi…
Mar 2025 DOI 10.14302/issn.2641-9467.jgrc-24-5386
Zhongsheng GuoCorresponding author
Farming development has gone through a long process. After a review of literatures, the results showed that according to the efficiency of resource utilization by plants, the whole process of farming development can be divided into three stages, the whole process of farming development can be divide…
Sep 2024 DOI 10.14302/issn.2692-1537.ijcv-24-5218
Cesar Luna-RiveroCorresponding author
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection often causes coagulation disorders that affect highly vascularized organs, such as the lungs and kidneys. Objective The objective of this study was to report the histopathological findings of variations in the fibrin p…
Sep 2024
Yong MaCorresponding author
A new approach to protecting the side chain of lysine during solid-phase peptide synthesis in an aqueous environment is explored. The objectives of this study are twofold: 1) to reduce the consumption of chemical solvents in peptide synthesis, and 2) to lower the costs associated with lysine side ch…
Aug 2024 DOI 10.14302/issn.2470-0436.jos-24-5162
João Alves AmbrósioCorresponding author
Introduction Cystoid macular edema (CME) is a sight-threatening condition caused by fluid accumulation in the macula due to blood-retinal barrier disruption. Various factors, including drug reactions, can lead to retinal fluid leakage. Leflunomide, a disease-modifying anti-rheumatic drug, marked sig…
Apr 2024 DOI 10.14302/issn.2690-4721.ijcm-24-5030
John S. GunnCorresponding author
Typhoid fever, caused by the human restricted pathogen Salmonella Typhi, remains a major global public health concern. Even after successful treatment, approximately 3-5% of patients with typhoid fail to clear the bacteria within one year and become chronic carriers. Most typhoid carriers have galls…
Feb 2024 DOI 10.14302/issn.2381-862X.jwrh-24-4918
Jennifer Chinoye AmadiCorresponding author
Access to sexual and reproductive healthcare for sexual minority women is essential to fulfilling their human rights. This qualitative study was conducted in Rivers State, Nigeria, with fifteen participants as key informants. The study addressed the barriers to the sexual and reproductive healthcare…
Jan 2024 DOI 10.14302/issn.2574-4496.jtc-23-4835
Abbas Hussein Saleh HusseinCorresponding author
The prevalence of thyroid cancer is rapidly increasing worldwide, majorly due to overdiagnosis and overtreatment methods of differentiated thyroid cancer. The emergent and potent preclinical models, high-throughput molecular techniques, and genetic expression microarrays have delivered deeper insigh…
Jan 2024 DOI 10.14302/issn.2374-9431.jbd-23-4842
Samer Wissam YounesCorresponding author
Over the past 20 years, the number of persons with diabetes has more than doubled globally. The purpose of this review article is to investigate the connection between certain vitamins and diabetes. Diabetes patients have been found to have decreased amounts of certain antioxidant vitamins including…