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May 2026 DOI 10.14302/issn.2572-3030.jcgb-26-6307
Arne-C. FaisstCorresponding author
The development of tumor biomarkers derived from blood, or its components, has become pivotal in advancing early cancer diagnosis. Malignant transformations induce cancer-specific alterations in the transcriptome, proteome, and secretome of tumor cells. Recent studies highlighted similar alterations…
Mar 2026 DOI 10.14302/issn.2994-6743.ijstd-26-6060
Pier Francesco AmadeoCorresponding author
Objective To describe the clinical features and real-world treatment of people living with human immunodeficiency virus (PLHIV) using fixed-dose or free combinations of 2-drug regimens (2DR) of antiretroviral therapy (ART). Design Italian retrospective cohort study. Methods Data were extracted from…
Dec 2025
Yilkal Tariku BelayCorresponding author
Background Research and drug development industries have multiphase drug screening procedures, which can be debated. As a result, harmful products may still reach for public health service delivery due to vulnerabilities in the process. Main body A wide range of test compounds have delayed manifesta…
May 2025 DOI 10.14302/issn.2641-5526.jmid-25-5466
John McCueCorresponding author
Information on adverse drug event (ADE) assessment and prevention within Electronic Health Records (EHRs) is difficult for clinicians to use and produces wide-ranging results. Challenges include inconsistent ADE and drug product definition and documentation, workflows, terminology standardization, i…
Apr 2024 DOI 10.14302/issn.2574-4526.jddd-24-4996
Rehan HaiderCorresponding author
The General Accounting Office released a study in August 1992 of twenty-nine sampled prescription drugs that reported an average increase in the price of approximately 138 percent between 1985 and 1991 (GAO 1992, 4, Table 1) Those and other published price indexes are increasingly being used in the…
Jan 2024 DOI 10.14302/issn.2642-9241.jrd-23-4809
Kadiatou SamakeCorresponding author
Introduction People living with HIV (PLHIV) are susceptible to developing non- communicable chronic respiratory diseases. Our objective was to study the spirometric profile of this population. Material and methods This was a descriptive and analytical cross-sectional retro-prospective study conducte…
Dec 2023 DOI 10.14302/issn.2324-7339.jcrhap-23-4634
Alfred MakuraCorresponding author
Introduction Human Immunodeficiency Virus (HIV) remains a persistent global public health challenge. In 2020, approximately 37.9 million individuals were living with HIV globally, including 1.7 million children <15 years old, with a global HIV prevalence of 0.8% among adults. A larger portion of peo…
Sep 2023
Hiroyuki SuzukiCorresponding author
Objectives The number of cases of cyanoacrylate closure (CAC) system for varicose veins has been increasing worldwide. However, as this is a new treatment method, the potential adverse effects and other details remain unclear. In particular, the cause of inflammation in embolized veins is still unde…
Feb 2023 DOI 10.14302/issn.2641-4538.jphi-23-4452
Lucio MangoCorresponding author
Interruptions during pharmacological therapy in a hospital ward can be a source of error. We therefore considered two Operating Units of a hospital by asking the following questions: are the nursing staff who administer drug therapy at the set times able to do so with maximum concentration and witho…
Dec 2022 DOI 10.14302/issn.2328-0182.japst-22-4363
Nikita S. PatilCorresponding author
The process of creating new pharmaceuticals is incredibly costly and time-consuming, and it dates back millions of years to the time when only herbal remedies were used. Furthermore, the solvation energies of the ligand and receptor site are crucial to this process because partial to complete dedica…
Sep 2020 DOI 10.14302/issn.2328-0182.japst-20-3526
Anbessa BekeleCorresponding author
Background Self-medication (SM) can be defined as the use of drugs to treat self-diagnosed disorders or symptoms, or the intermittent or continued use of a prescribed drug for chronic or recurrent disease or symptoms. A number of individuals in developing countries do not attend physicians for their…
Sep 2020 DOI 10.14302/issn.2835-513X.ijl-20-3470
Anju GuptaCorresponding author
This review discusses lipid assemblies—from liposomes to solid lipid nanoparticles—as platforms for drug delivery. It covers design principles, targeting strategies, and manufacturing considerations.
Jul 2019
Shivaji K JadhavCorresponding author
Co-infection of HIV with Mycobacterium tuberculosis is a common event, particularly in developing countries. The emergence and spread of multidrug resistant tuberculosis (MDR-TB) is an increasing public problem in India. The drug-resistant M. tuberculosis strains are posing a significant challenge t…
May 2019 DOI 10.14302/issn.2574-4526.jddd-19-2770
Andre-Jean RemyCorresponding author
Introduction In France 33% of patients didn’t take care of hepatitis C because there were no diagnosed. Drug injection was main contamination route of hepatitis C virus (HCV) in France. French guidelines were to treat all inmates and drug users, even fibrosis level. Access of HCV screening, care and…
Feb 2019 DOI 10.14302/issn.2470-5020.jnrt-19-2618
Naiya PatelCorresponding author
Objective Testing a new drug, treatment, and medical device clinically is critically important before prescribing it to patient. Not determining the drug’s safety and efficacy through clinical trials might impose life threatening outcomes on its consumers. The research paper describes the critical f…
Dec 2018 DOI 10.14302/issn.2578-8590.ipj-18-2524
Francesco CrespiCorresponding author
The pineal gland constitutes a major neuroendocrine organ in the brain. By mean of its neurohormone melatonin it transduces exogenous signals such as circadian and seasonal variations of light and temperature into proper hormonal changes which adjust and adapt internal endocrine functions. Alteratio…
Nov 2018 DOI 10.14302/issn.2324-7339.jcrhap-18-2291
Yahya Muhammed BahCorresponding author
In The Gambia like all nations, drug abuse is seen as a social and health problem that has many serious implications for the physical, social, psychological and intellectual development of the victims more especially, the children. Therefore, it continues to be a concern to families, community leade…
Aug 2018
Qifeng BaiCorresponding author
Drug design, referred to the fields of pharmacology, biotechnology and medicine, is in silico, in vitro and in vivo assay processes of finding new candidate medications based on the biological targets. The in silicoexperiments of drug discovery are involved in the macromolecular structure databases,…
May 2018 DOI 10.14302/issn.2473-1005.jdoi-18-2115
Muhammad ZahoorCorresponding author
Background: The human mouth harbors over 700 microbial genera. The large number of them is normal bacteria; few of them are opportunistic pathogens. Objective: The study was aimed to evaluate the bacterial population of drug addicted persons and compare it to that of a normal healthy person. Methods…
May 2018 DOI 10.14302/issn.2578-8590.ipj-18-2113
Rahul HajareCorresponding author
Isatin (1H-indole-2,3-dione ) and derivatives demonstrate a diverse array of biological activities. Isatin and 5-halo derivatives has reacted to form the schiff’s bases , mannich bases and friedal craft alkylation’s to form C-C, C-N, C=N bonds. From the spectral studies, isatin has undergoes reactio…