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Feb 2022 DOI 10.14302/issn.2379-8572.joa-22-4072
Pier Mario BiavaCorresponding author
This translational paper discusses differentiation‑stage factors from zebrafish embryos as epigenetic regulators with potential to reverse neurosensory hearing loss. It outlines experimental evidence, delivery concepts, and research gaps.
May 2015 DOI 10.14302/issn.2379-7835.ijn-14-603
Kenneth LundstromCorresponding author
Epigenetic mechanisms based on DNA methylation, histone modifications and RNA interference have recently showed important association to the development of a wide variety of diseases such as cancer, cardiovascular, metabolic, skin, autoimmune diseases and neurologic disorders. In the context of prev…
Mar 2021 DOI 10.14302/issn.2329-9487.jhc-21-3742
Tesfaye SisayCorresponding author
Cardiovascular disease is actually a major cause of mortality, illness and hospitalization worldwide. Several risk factors have been identified that are strongly associated with the development of cardiovascular disease. Public prevention strategies have relied predominately on managing environmenta…
Jun 2019 DOI 10.14302/issn.2688-5328.ijp-19-2731
Xiang WeiCorresponding author
The rise of epigenetics provides a new idea for studying the regulation of chronic pain-related genes and synaptic plasticity. External environmental stimuli can regulate BDNF genes through different epigenetic modifications. The epigenetic changes of the BDNF gene can affect the expression of its m…
Aug 2018 DOI 10.14302/issn.2689-4602.jes-18-2229
George MikhailovskyCorresponding author
A historical and conceptual review traces how evolutionary theory has expanded from classical selection to modern syntheses incorporating development, epigenetics, and systems thinking. Implications for research and science communication are discussed.
May 2018
Ioannis AlatsathianosCorresponding author
Genetics alone cannot thoroughly expound the environmental impact on the molecular complexity of the endocrine system. Epigenetic-induced alteration in gene expression has emerged as a way in which environmental compounds may exert endocrine effects. The environmental compounds that interfere with n…