Search results for “hypothesis”

About 29 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching hypothesis — open any to read the full text, or download the PDF or XML.

From Pelvis to Foot, Part II: A Longitudinal Kinetic Chain Hypothesis for Eversion Ankle Sprains in Athletes

Aug 2026 DOI 10.14302/issn.2694-2283.jsem-26-6342
Gabriel QuinteroCorresponding author

Background Eversion ankle sprains, although less common than inversion injuries, are often associated with greater severity and more complex recovery patterns. Their biomechanical origin remains less clearly understood. Objective To propose a functional, longitudinal kinetic chain model in which ant…

Neuroscience Theories, Hypothesis and Approaches to ASD Physiopathology. A Review

Aug 2019 DOI 10.14302/issn.2470-5020.jnrt-19-2974
OJ CastejónCorresponding author Instituto de Investigaciones Biológicas “Drs. Orlando Castejón and Haydee Viloria de Castejón” e Instituto de Neurociencias Clínicas, Fundación Castejón, San Rafael Clinical Home. Maracaibo. Venezuela.

According to the results of our laboratory the theory of immune dysfunction, the theory on the genetic architecture of ASD, the disrupted cortical connectivity theory and the theory on the contribution of cerebellum to ASD have shown fundamental experimental evidences to support the core symptoms of…

The Pineal Hypothesis for Drug Dependence

Dec 2018 DOI 10.14302/issn.2578-8590.ipj-18-2524
Francesco CrespiCorresponding author

The pineal gland constitutes a major neuroendocrine organ in the brain. By mean of its neurohormone melatonin it transduces exogenous signals such as circadian and seasonal variations of light and temperature into proper hormonal changes which adjust and adapt internal endocrine functions. Alteratio…

Raising HLA-E-Restricted HIV-1-Specific Immune Responses Through T Cell Vaccination: A Hypothesis

Jun 2017 DOI 10.14302/issn.2690-4721.ijcm-17-1533
Soon Hoe Ho BSc (Hon)Corresponding author

This essay draws on recent evidences from SIV vaccination studies in rhesus macaques to argue for the potential importance of HIV-1-specific CD8+ T cells restricted by the non-classical major histocompatibility complex, HLA-E, in controlling HIV-1 replication. It then seeks to present a possible met…

Rescuing Canavan Disease by Redirecting Metabolic Processing: Support for the Astrocyte Hypothesis of Canavan Disease Generation and A Possible Human Cure

Apr 2017 DOI 10.14302/issn.2572-5424.jgm-17-1482
Morris H BaslowCorresponding author

Canavan disease (CD) is a globally occurring but rare human spongiform leukodystrophy that is associated with inborn errors affecting the activity of aspartoacylase (ASPA), an enzyme highly expressed in oligodendrocytes that hydrolyzes N-acetylaspartate (NAA). Lack of ASPA activity is associated wit…

From Pelvis to Foot: A Functional Approach to Preventing Ankle Sprains in Athletes

Jun 2026 DOI 10.14302/issn.2694-2283.jsem-26-6247
Gabriel QuinteroCorresponding author

Background Ankle sprains are among the most common injuries in sports, often characterized by high recurrence rates despite appropriate local treatment. Traditional approaches primarily focus on the injured joint, with limited attention to proximal biomechanical factors that may predispose athletes…

Traumatic Maculopathy (Berlin´S Edema) Treated with Enhancement of Human Photosynthesis®

Nov 2025 DOI 10.14302/issn.2474-7785.jarh-25-5760
Arturo Solís HerreraCorresponding author

Commotio retinae (CR) is a condition frequently observed in clinical practice, particularly following closed globe trauma (CGT) due to sport, labor, or traffic accident injuries. It is the main cause of unilateral vision loss in male patients aged between. It is characterized by transient gray-white…

Peripheral Third Cranial Nerve Palsy in A Patient With Pediatric Form of Multiple Sclerosis

Jun 2024
Abdallah RahbaniCorresponding author

Multiple Sclerosis has traditionally been considered an inflammatory and autoimmune disease of the central nervous system. However, peripheral cranial nerve involvement has been described previously in eight cases, raising the hypothesis of a disease spectrum between central and peripheral nervous s…

The Sweet and Sour of the Sugar-Sweetened Beverage Tax

Apr 2021 DOI 10.14302/issn.2379-7835.ijn-21-3780
Khamis Al-AlawyCorresponding author Mohammad Bin Rashid School of Government, Dubai, UAE

Obesity is a common and preventable Non-Communicable Disease that is of great importance. Population-based interventions are recognised to have a profound effect on improving health outcomes. One of these approaches includes the adoption of the Sugar-Sweetened Beverage (SSB) Tax. Objectives There we…

The Role of Health on Economic Development.

Dec 2020 DOI 10.14302/issn.2997-1969.ijhs-20-3658
Assan JallowCorresponding author PhD student at the rome school of Economics Italy

In this project the main aim is to investigate the role of health on economic development. In doing so my inspiration was derive for the augmented neoclassical theoretical firm work base on the hypothesis that health has a positive impact on economic growth, looking at specification 1 and 4 are basi…

UV rays Decrease Foliar pH in Cress (Lepidium Sativum) and Modify NIR Spectrum

Dec 2020 DOI 10.14302/issn.2639-3166.jar-20-3639
Giorgio MasoeroCorresponding author

An experiment on watercress (Lepidium sativum) 42 d days after sowing was set up to evaluate the effect of UVAB radiation on foliar pH and on NIR tomoscopy. The effect of 8 h of UV exposure (about 500 µWcm-2) was clear, causing a reduction in the foliar pH of 6.0%, compared to the contemporary contr…

A Case Report on Challenging Management of Multiple Neoplasms in Elderly

Dec 2020 DOI 10.14302/issn.2474-7785.jarh-20-3628
Syiao Wei NgCorresponding author Hospital Sultanah Aminah, Jalan Persiaran Abu Bakar Sultan, 80100 Johor Bahru, Johor, Malaysia

Multiple primary malignancies especially in the head and neck region is no longer a rare occurrence and the prevalence is increasing. They were described as synchronous when the malignancies present within 6 months of another or metachronous tumors if the subsequent malignancy presents 6 months late…

Perceived Effect of Knowledge Level and Socio-Demographics on COVID-19 Risk Exposure: the Africa Experience

Nov 2020 DOI 10.14302/issn.2692-1537.ijcv-20-3620
Obioma AzuonwuCorresponding author Department of Medical Laboratory Science, Medical Bacteriology / Virology / Parasitology Unit, Rivers State University, Nkpolu – Oroworukwo, Port Harcourt, Rivers State, Nigeria.

COVID-19 remains a global public health emergency till date. It is eminent that the transmission of the disease is subjective to people’s readiness to implement public health preventative strategies and these are often related to knowledge. Proper public knowledge about COVID-19 plus its predisposin…

Animals in the COVID-19 Era: Between Being a source, Victims, or Maybe our Hope to Overcome it!

Sep 2020 DOI 10.14302/issn.2692-1537.ijcv-20-3481
Shilpi GuptaCorresponding author

The indirect misuse of animals usually correlated to catastrophic consequences like the one we are facing now, novel coronavirus disease-19. However, the source of infection is not fully confirmed yet. But the finger of blame points to bats and pangolins. Hence, understanding and raising awareness a…

Molecular Study of Hepcidin HAMP (-582A/G) Gene Polymorphisms and Measurement of Serum Hepcidin Level among Sudanese Patients with Anemia of Chronic Kidney Disease

May 2020 DOI 10.14302/issn.2575-7881.jdrr-20-3343
Amged Hussen AbdelrhmanCorresponding author

Background Anemia of chronic disease is anemia found in certain chronic disease states, is typically marked by the disturbance of iron homeostasis or hypoferremia. Chronic renal failure is currently known as Chronic Kidney Disease (CKD) or Chronic Renal Insufficiency (CRI) implies long-standing, pro…

The Mechanism of Decline of Senescent Skeletal Muscle Satellite Cell Self-Renewal and Regenerative Proliferation: The Role of Heparan Sulfate-FGF-2--FGFR1-p38αMAPK Axis, Sprouty1, miR-1, miR-133 and miR-29a

Apr 2020 DOI 10.14302/issn.2832-4048.jsm-20-3211
John PapaconstantinouCorresponding author

Aging mammalian skeletal muscle satellite cells (MuSCs) undergo a decline of stem cell/progenitor cell proliferative and regenerative capacity, and the development of a physiological milieu characteristic of a state of chronic sterile inflammation. p38αMAPK and ERK1/2 are two major signaling pathway…

Evaluation of cardiorespiratory parameters in dogs undergoing laparoscopic versus open gonadectomy with spontaneous ventilation anaesthesia: a pilot study

Mar 2020 DOI 10.14302/issn.2575-1212.jvhc-20-3256
Fabrizio di VirgilioCorresponding author

This pilot study aims to compare cardiorespiratory parameters in female dogs that underwent either laparoscopic or open elective gonadectomy with spontaneous ventilation anaesthesia. Records of 77 client-owned female dogs were reviewed. Patients were divided into two groups: laparoscopic surgery (L…

Abelmoschus Esculentus (Moench.) Seed Derived Flavonoids Antioxidant Protect the Heart Against Experimental Oxidative Injury

Mar 2020 DOI 10.14302/issn.2577-2279.ijha-20-3215
O. Atinuke AnjorinCorresponding author Department of Anatomy and Cell Biology

Since oxidative stress impairs the cardiovascular function, the hypothesis from the present study is that the treatment of paraquat-exposed adult Wistar rats with methanolic extract of Abelmoschus esculentusseed would reduce paraquat-induced cardiovascular damage. Thirty healthy female Wistar rats w…

Sunspots are Correlated with Foliar pH in Grapevines

Dec 2019 DOI 10.14302/issn.2639-3166.jar-19-3116
Giorgio MasoeroCorresponding author

Foliar pH is a specific multifaceted parameter that is sensitive to a deficit in soil water and to temperature variations. It also represents a tool that can be used to rapidly phenotype the symbiosis induced in several crops by bio-fertilizers containing Arbuscular Mycorrhizal Fungi. Yearly decreas…

A Comparative Study of the Impact of Himalayan Singing Bowls and Supine Silence on Stress Index and Heart Rate Variability

Oct 2019 DOI 10.14302/issn.2474-9273.jbtm-19-3027
Gunjan Y TrivediCorresponding author

Introduction Sound vibrations have a profound impact on the body and the mind with evidence confirming reduced anxiety and increased wellbeing. The likely reason for driving the benefit is relaxation. The Himalayan Singing Bowls, used for therapeutic intervention to enhance the individual’s emotiona…

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