Search results for “miRNA”

About 11 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching miRNA — open any to read the full text, or download the PDF or XML.

The Use of Mirnas as Activators of Dental Implant Surfaces, A Review

Sep 2018
Riccardo Di GianfilippoCorresponding author

MicroRNAs are short sequences of non-coding RNAs crucial in regulation of cell development, proliferation and differentiation. Some of them showed to be related with the expression of osteogenic genes. Aim of the present review was to evaluate the biological effects of titanium implant surfaces acti…

Dynamic MicroRNA-Expression in Plasma of Melanoma Patients Correlates With Progression, PD-L1 Status and Overall Survival

Mar 2024 DOI 10.14302/issn.2572-3030.jcgb-24-4970
Sarah DegenhardtCorresponding author

Melanoma treatment has improved significantly with the development of immune checkpoint inhibition (ICI), which has greatly enhanced the survival rates of patients with metastatic melanoma. However, a significant number of patients do not respond well to ICI treatment and experience progression. Thi…

A Summary of Circular RNAs in Alzheimer's Disease

Jan 2021 DOI 10.14302/issn.2470-5020.jnrt-20-3619
Keping ChenCorresponding author

Circular RNAs (circRNAs) are recently rediscovered eukaryotic molecules that form a covalently closed-loop structure through a special type of alternative splicing known as backsplicing. These closed-loop structures are highly stable and resistant to RNase degradation, and are thereby expressed in a…

Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings

Oct 2020 DOI 10.14302/issn.2379-7835.ijn-20-3418
Farid E. AhmedCorresponding author

Isolation methods that employ readily-available inexpensive supplies on the open market, which are reliable, as well as economical, such as nucleic acid amplification techniques (NAAT) based on microfluidic technology in low-resource research settings (LRRS) that meets the ASSURED guidelines are ess…

Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings

Jun 2020 DOI 10.14302/issn.2379-7835.ijn-19-3123
Farid E. AhmedCorresponding author

Isolation methods that employ readily-available inexpensive supplies on the open market, which are reliable, as well as economical, such as nucleic acid amplification techniques (NAAT) based on microfluidic technology in low-resource research settings (LRRS) that meets the ASSURED guidelines are ess…

Developing Cellular & Molecular Biomarkers for Anti-Inflammatory Activities of Probiotic Bacteria in Fermented Foods

Mar 2019 DOI 10.14302/issn.2379-7835.ijn-19-2578
Farid E. AhmedCorresponding author

We present below a mechanistic cellular and molecular approaches for the development of Anti-Inflammatory biomarkersof Probiotic Bacteria in Fermented Foods. Probiotics are live microorganisms that promote human health by counteracting the noxious toxic gut microflora in human intestine, by modulati…

Quantification of Micrornas by Absolute Dpcr for the Diagnostic Screening of Colon Cancer

Feb 2019 DOI 10.14302/issn.2471-7061.jcrc-18-2526
Farid E. AhmedCorresponding author

There is currently no validated micro(mi)RNA diagnostic stool test to screen for colon cancer (CC) on the market because of the complexity of fecal density, vulnerability of stool to daily changes, and the presence of three sources of miRNAs in stool (cell-free from fecal homogenates, exsosomal miRN…

MicroRNA: New Era for Therapeutic Strategy in Ischaemic Heart Disease

Jun 2017 DOI 10.14302/issn.2329-9487.jhc-17-1536
Md. Kamrul HossainCorresponding author

Over the last few decades, many research works highlighted the role of miRNAs on cardiac diseases. Ischaemic heart disease (IHD) or coronary heart disease is a condition that is mainly caused by atherosclerosis. It has been established that microribonucleic acids regulate many factors that are invol…

MicroRNAs: As A Novel Potential Tool for Diagnosis, Prognosis, and Therapeutic Agents in Hypertension.

Oct 2015 DOI 10.14302/issn.2329-9487.jhc-15-677
Ravindra KolheCorresponding author

The aim of this review is to compile our understanding of microRNA (miRNA) and its significance in Hypertension (HTN) pathophysiology. The wide spectrum of health disparity is one of the reasons for the dominance of HTN in humans for decades. We are striving hard to understand these variations, and…

MicroRNA Profiling of Differentiated, Poorly Differentiated and Anaplastic Thyroid Carcinoma, a Comparative Approach

May 2015 DOI 10.14302/issn.2572-3030.jcgb-14-495
Ashraf KhanCorresponding author

Thyroid carcinomas encompass a wide spectrum ranging from differentiated thyroid carcinoma (DTC) to poorly differentiated (PDC) and anaplastic thyroid carcinoma (ATC). DTC of both follicular (FTC) and papillary (PTC) types can progress to PDC and AC. The aim of our study was to evaluate if there is…

Epigenetics and Nutrition

May 2015 DOI 10.14302/issn.2379-7835.ijn-14-603
Kenneth LundstromCorresponding author

Epigenetic mechanisms based on DNA methylation, histone modifications and RNA interference have recently showed important association to the development of a wide variety of diseases such as cancer, cardiovascular, metabolic, skin, autoimmune diseases and neurologic disorders. In the context of prev…

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