Journal of New Developments in Chemistry
Open Access
Development of Poly-ε-Caprolactone Based Nanoadjuvant for Effective Vaccination Against Tuberculosis
Apr 2014 DOI 10.14302/issn.2377-2549.jndc-13-329
Amit Kumar DindaCorresponding author
The aim of the study was to synthesize sub-100nm poly-ε-caprolactone nanoparticles (PCL NP), load them with the mycobacterial protein, ESAT 6 and study the resulting immune responses in CD4+ and CD8+ T cells when incubated with human peripheral blood monocyte derived macrophages that had internalize…