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Aug 2026 DOI 10.14302/issn.2377-2549.jndc-26-6392
Grigorii G. SivetsCorresponding author
Chemoenzymatic synthesis of a series of purine modified 3′ deoxyribonucleosides was studied from purine derivatives as acceptors and an excess of 3′-deoxyuridine as the donor, prepared by the chemical deamination of 3′-deoxycytidine, using recombinant uridine and purine nucleoside phosphorylases as…
Nov 2025 DOI 10.14302/issn.2474-7785.jarh-25-5760
Arturo Solís HerreraCorresponding author
Commotio retinae (CR) is a condition frequently observed in clinical practice, particularly following closed globe trauma (CGT) due to sport, labor, or traffic accident injuries. It is the main cause of unilateral vision loss in male patients aged between. It is characterized by transient gray-white…
Jul 2025 DOI 10.14302/issn.2377-2549.jndc-25-5525
Grigorii G. SivetsCorresponding author
A stereoselective synthesis of N-glycosyl amides was studied from available N-glycosyl oxazolines prepared by Ritter-like reactions of protected sugar acetonides. Hydrolysis reactions of the protected pentofuranosyl and hexafuranosyl oxazolines, as precursors of glycosyl amine derivatives, were carr…
Sep 2024
Yong MaCorresponding author
A new approach to protecting the side chain of lysine during solid-phase peptide synthesis in an aqueous environment is explored. The objectives of this study are twofold: 1) to reduce the consumption of chemical solvents in peptide synthesis, and 2) to lower the costs associated with lysine side ch…
Apr 2024
Yong MaCorresponding author
A procedure has been developed for synthesizing peptides in an aqueous solution with a reusable solid phase. Specifically designed linker molecule is employed to attach peptides to hydrophilic solid phases, enabling Solid Phase Peptide Synthesis (SPPS) in aqueous solutions. The linker molecule is ut…
Dec 2023 DOI 10.14302/issn.2377-2549.jndc-23-4740
Grigorii G. SivetsCorresponding author
A stereoselective synthesis of protected N-glycosyl oxazolines has been developed from available acylated sugar 1,2-O-acetonides using intramolecular Ritter-like reactions. New N-α- and β-D-pentofuranosyl, α-D-hexofuranosyl oxazolines as valuable intermediates for preparation of diverse N-glycosides…
Dec 2021 DOI 10.14302/issn.2766-8681.jcsr-21-3805
Chiaa AdicheCorresponding author
A convenient one-pot synthetic protocol for the preparation of sulfonyl amidines has been developed. The procedure combines three-component reaction of sulfonyl azide, methyl propiolate and secondary cyclic amine coupling in one sequence without any solvent or catalyst and at room temperature. The r…
Nov 2021 DOI 10.14302/issn.2377-2549.jndc-21-4017
Grigorii SivetsCorresponding author
Theefficient two-step synthesis of 2-chloro-2′-deoxyadenosine (cladribine) via the anion glycosylation of purine potassium salt with the glycosyl chloride in binary solvent mixtures is described. A new method for preparation of diprotected 2-chloro-6-fluoropurine 2′-deoxy-β- D-riboside was developed…
Dec 2018 DOI 10.14302/issn.2328-0182.japst-18-2522
Priyanka KumawatCorresponding author
The solid copper(II) soap derived from Neem (Azadirechta Indica)oil and its complex with ligand containing nitrogen, sulphur and oxygen atoms like 2-amino -6-nitro benzothiazole and 2-amino- 6-ethoxy benzothiazole have been synthesized and characterised by elemental analysis, IR spectroscopy and bio…
Sep 2017 DOI 10.14302/issn.2575-7881.jdrr-17-1749
Kiran D. BhilareCorresponding author
Though, directed evolution/In vitro evolution has greatly enhanced the applicability of natural biomolecules, there is still a big void in synthetic biology, which could be filled only when we are able to make novel/synthetic functional biomolecules. Terminal deoxyribonucleotidyl transferase (TdT) i…
Jul 2017 DOI 10.14302/issn.2639-1716.jn-17-1495
Michael J GonzalezCorresponding author
Diets high in unsaturated fatty acids, especially those containing high levels of linoleic acid, e.g., corn oil, enhance mammary gland tumorigenesis in experimental animals. In contrast, diets high in long-chain polyunsaturated fatty acids such as eicosapentaenoic (EPA) and docosahexaenoic (DHA), e.…
Mar 2017 DOI 10.14302/issn.2572-5424.jgm-16-1352
Syed Qaiser ShahCorresponding author
In this investigation, Rifabutin dithiocarbamate (RFND) was labeled with Technetium-99m (99mTc) using tricarbonyl technique. The labeled RFND was further characterized in terms of radiochemical purity, stability in saline & serum, in vitro bacterial binding, biodistribution in animal model rats and…
Oct 2016 DOI 10.14302/issn.2572-5424.jgm-16-1170
Gul Majid KhanCorresponding author
Background: Skin is one the most important sites for administration of drugs to obtain desired pharmacological effects either locally or through systemic bioavailability; and this has placed the transdermal route of drug delivery as an attractive and as one of the most innovative areas for conductin…
Oct 2026 DOI 10.14302/issn.2329-9487.jhc-26-6071
Eujin Min Houng ChoyCorresponding author
Background: Shift work is unavoidable in continuous healthcare delivery, but whether shift-working healthcare staff carry greater cardiovascular risk than their non-shift colleagues has not been synthesised endpoint by endpoint. Objective: To examine, for each cardiovascular risk factor and each cli…
Aug 2026 DOI 10.14302/issn.2998-1506.jpa-26-6394
Snehasis JanaCorresponding author
Background Enhancing crop productivity while minimizing chemical inputs remains a core objective of sustainable agriculture. This study investigated the efficacy of spiritual blessing energy treatments as a non-invasive biostimulant to optimize the growth dynamics and crop yield of radish (Raphanus…
Feb 2026 DOI 10.14302/issn.2689-4602.jes-25-5926
Chuck EasttomCorresponding author
The impact of ionizing radiation on genetic change is well established, yet the extent to which naturally occurring radiation fields have influenced evolutionary trajectories remains incompletely understood. This study examined correlations between microbial evolution and the radiation and geochemic…
Nov 2025 DOI 10.14302/issn.2574-612X.ijpr-25-5771
Anthony CameronCorresponding author
This article offers a literature review and theoretical synthesis and application of existential therapy and the contextual model. It reviews the contextual factors that may be predictive of positive therapy outcomes in general, identifies distinct types of existential therapy, highlights core commo…
Nov 2025 DOI 10.14302/issn.2326-0793.jpgr-25-5573
Oghenetega E. ImiruayeCorresponding author
Advancements in proteomic and genomic technologies have transformed molecular biology by enabling comprehensive analysis of biological systems at the molecular level. This literature review explores the evolution, methodologies, and practical applications of key proteomic and genomic techniques. In…
Oct 2025 DOI 10.14302/issn.3070-3360.ijco-24-5294
Rameshwar AdhikariCorresponding author
Ayurveda is a traditional and scholarly medical system practiced in South Asia since the Vedic period. It integrates science and philosophy to promote a healthy, happy and prosperous life. Ayurvedicbhasmas are classical formulations that contain non-toxic forms of metals and minerals, enriched with…
Aug 2025 DOI 10.14302/issn.3070-1937.ijbt-25-5540
Mbacham Harry FonCorresponding author
The rising need for structured and efficient blood transfusion services in low-resource settings has driven the adoption of collaborative blood transfusion management systems (CBTMS). This study explores the functionality and impact of the Cornerstone University Blood Management System version 1.0 (…