Overview
Retinal vein occlusion (RVO) is a common retinal vascular disorder caused by thrombotic blockage of a vein draining the retina, leading to raised venous pressure, haemorrhage, retinal oedema, and ischaemia that can impair vision. It is classified by the site of obstruction into central retinal vein occlusion (CRVO), affecting the main vein at the optic nerve head, and branch retinal vein occlusion (BRVO), affecting a tributary vein, usually at an arteriovenous crossing. Vision loss results chiefly from macular oedema and, in ischaemic forms, from retinal and anterior-segment neovascularization. Established risk factors include hypertension, diabetes, and thrombophilic and hypercoagulable states. This topic spans the presentation, systemic associations, and management of RVO. Relevant work documents central retinal vein occlusion arising in the setting of hepatocellular carcinoma and branch retinal vein occlusion associated with a Factor V Leiden mutation, illustrating links to underlying systemic and prothrombotic disease. Related research examines occlusive events tied to plasminogen-activator-inhibitor mutations and compares treatment strategies, including combined anti-vascular endothelial growth factor (anti-VEGF) therapy with corticosteroids versus anti-VEGF alone for the resulting macular oedema. Together these studies underscore the value of evaluating systemic risk factors alongside ophthalmic treatment of the retinal complications.
Research published in this journal
7 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Branch Retinal Vein Occlusion in Factor V Leiden Mutation
Compression between Combined Anti-VGEF with Steroids Versus Pure Anti-VEGF in Retinal Vein Occlusion
Recurrent branch retinal arterial occlusions associated with plasminogen activator inhibitor-1 mutation
Rapidly Progressing Visual Loss Associated with Optic Nerve Head Drusen: Is there A Role For Lowering Intraocular Pressure?
How this research is being cited
The 7 articles above have been cited 28 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.
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2026 · Journal of Clinical Ophthalmology and Research
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2026 · Advances in Ophthalmology and Optometry
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2026 · Advances in Ophthalmology and Optometry
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2026 · Journal of Clinical Ophthalmology and Research
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2025 · Journal of Liver Cancer
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2025 · Journal of Liver Cancer
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S. Sanjay et al. · 2023 · Medical hypothesis, discovery & innovation in optometry
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2023 · Medical Hypothesis Discovery & Innovation in Optometry
A sample of recent works citing this journal's research on Retinal Vein Occlusion, linking to each citing work.